Income Taxes (Details) - USD ($) $ in Thousands |
12 Months Ended | |
|---|---|---|
Dec. 31, 2021 |
Dec. 31, 2020 |
|
| Operating Loss Carryforwards [Line Items] | ||
| Federal statutory income tax rate | 21.00% | 21.00% |
| Federal Operating loss carryforwards | $ 534,200 | |
| State Operating loss carryforwards | 534,800 | |
| Federal Operating loss carryforwards subject to expiration | 37,200 | |
| Federal Operating loss carryforwards subject to expiration indefinitely | 497,000 | |
| Research and development tax credit carryforwards | 36,161 | $ 23,524 |
| Increase in gross deferred tax assets, before valuation allowance | 65,800 | |
| Accrued interest or penalties | 0 | 0 |
| Uncertain tax positions | 0 | $ 0 |
| U.S. federal | ||
| Operating Loss Carryforwards [Line Items] | ||
| Research and development tax credit carryforwards | 22,700 | |
| State | ||
| Operating Loss Carryforwards [Line Items] | ||
| Research and development tax credit carryforwards | $ 15,600 | |