Property, plant and equipment, net consisted of the following (in thousands): | | | | | | | | | December 31, | | | 2021 | | 2020 | Land | | $ | 1,300 | | $ | 1,300 | Manufacturing facility | | | 33,203 | | | 30,969 | Manufacturing equipment | | | 8,831 | | | 8,782 | Laboratory equipment | | | 17,501 | | | 16,639 | Computer equipment | | | 2,645 | | | 2,118 | Furniture and fixtures | | | 1,281 | | | 1,228 | Leasehold improvements | | | 444 | | | 444 | Construction-in-progress | | | 4,181 | | | 2,605 | | | | 69,386 | | | 64,085 | Less: Accumulated depreciation and amortization | | | (17,856) | | | (10,133) | | | $ | 51,530 | | $ | 53,952 |
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