Royalty Pharma Holdings Ltd.

Notice of Effectiveness

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Prospectus filed pursuant to Rule 424(b)(3)

Prospectus filed pursuant to Rule 424(b)(3)

Prospectus filed pursuant to Rule 424(b)(5)

Prospectus filed pursuant to Rule 424(b)(5)

Automatic shelf registration statement of securities of well-known seasoned issuers

Prospectus filed pursuant to Rule 424(b)(3)

Registration of securities issued in business combination transactions

Registration of securities issued in business combination transactions