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Related Filers (45)

Financials (13)

10-Q
Thursday, 8/5/2021
Quarterly Report for period ending 2021-06-30
10-Q
Thursday, 5/6/2021
Quarterly Report for period ending 2021-03-31
10-K
Monday, 3/1/2021
Annual Report for period ending 2020-12-31
10-Q
Thursday, 11/5/2020
Quarterly Report for period ending 2020-09-30
10-Q
Thursday, 8/6/2020
Quarterly Report for period ending 2020-06-30
10-Q
Thursday, 5/7/2020
Quarterly Report for period ending 2020-03-31
10-K
Thursday, 3/12/2020
Annual Report for period ending 2019-12-31
10-Q
Wednesday, 11/6/2019
Quarterly Report for period ending 2019-09-30
10-Q
Wednesday, 7/31/2019
Quarterly Report for period ending 2019-06-30
10-Q
Thursday, 5/9/2019
Quarterly Report for period ending 2019-03-31
10-K
Thursday, 3/21/2019
Annual Report for period ending 2018-12-31
10-Q
Thursday, 11/8/2018
Quarterly Report for period ending 2018-09-30
10-Q
Thursday, 8/9/2018
Quarterly Report for period ending 2018-06-30
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News (32)

8-K
Tuesday, 9/14/2021
Current report filing
8-K
Tuesday, 8/3/2021
Current report filing
8-K
Wednesday, 6/16/2021
Current report filing
8-K
Tuesday, 4/20/2021
Current report filing
8-K
Tuesday, 3/23/2021
Current report filing
8-K
Thursday, 2/25/2021
Current report filing
8-K
Monday, 12/28/2020
Current report filing
8-K
Tuesday, 12/22/2020
Current report filing
8-K
Tuesday, 8/25/2020
Current report filing
8-K
Monday, 7/20/2020
Current report filing
8-K
Friday, 6/26/2020
Current report filing
8-K
Tuesday, 6/23/2020
Current report filing
8-K
Tuesday, 6/16/2020
Current report filing
8-K
Tuesday, 4/7/2020
Current report filing
8-K
Friday, 3/27/2020
Current report filing
8-K
Thursday, 3/26/2020
Current report filing
8-K
Monday, 1/13/2020
Current report filing
8-K
Thursday, 12/12/2019
Current report filing
8-K/A
Friday, 10/25/2019
Current report filing
8-K
Wednesday, 9/18/2019
Current report filing
8-K
Thursday, 9/12/2019
Current report filing
8-K
Wednesday, 7/31/2019
Current report filing
8-K
Monday, 7/15/2019
Current report filing
8-K
Wednesday, 6/19/2019
Current report filing
8-K/A
Wednesday, 6/19/2019
Current report filing
8-K/A
Wednesday, 6/19/2019
Current report filing
8-K
Wednesday, 5/1/2019
Current report filing
8-K
Thursday, 4/11/2019
Current report filing
8-K
Monday, 4/8/2019
Current report filing
8-K
Thursday, 1/3/2019
Current report filing
8-K
Monday, 7/9/2018
Current report filing
8-K
Monday, 7/2/2018
Current report filing
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Other (36)

15-12B
Friday, 9/24/2021
Notice of termination of registration of a class of securities under Section 12(b)
EFFECT
Tuesday, 9/21/2021
Notice of Effectiveness
EFFECT
Tuesday, 9/21/2021
Notice of Effectiveness
SC 14D9/A
Tuesday, 9/14/2021
Tender offer solicitation/recommendation statements filed under Rule 14d-9
POSASR
Tuesday, 9/14/2021
Post-effective Amendment to an automatic shelf registration statement on Form S-3ASR or Form F-3ASR
POS AM
Tuesday, 9/14/2021
Post-effective amendment to a registration statement that is not immediately effective upon filing
25-NSE
Tuesday, 9/14/2021
Notification filed by national security exchange to report the removal from listing and registration of matured, redeemed or retired securities
POSASR
Tuesday, 9/14/2021
Post-effective Amendment to an automatic shelf registration statement on Form S-3ASR or Form F-3ASR
POS AM
Tuesday, 9/14/2021
Post-effective amendment to a registration statement that is not immediately effective upon filing
SC 14D9/A
Tuesday, 9/7/2021
Tender offer solicitation/recommendation statements filed under Rule 14d-9
SC 14D9/A
Friday, 8/27/2021
Tender offer solicitation/recommendation statements filed under Rule 14d-9
SC 14D9
Monday, 8/16/2021
Tender offer solicitation/recommendation statements filed under Rule 14d-9
SC14D9C
Tuesday, 8/3/2021
Written communication by the subject company relating to a third party tender offer
CT ORDER
Tuesday, 5/18/2021
Order Granting Confidential Treatment
CT ORDER
Monday, 1/11/2021
Order Granting Confidential Treatment
EFFECT
Monday, 5/4/2020
Notice of Effectiveness
CORRESP
Thursday, 4/30/2020
A correspondence can be sent as a document with another submission type or can be sent as a separate submission.
SEC STAFF LETTER
Wednesday, 2/26/2020
None
SEC STAFF LETTER
Thursday, 2/13/2020
None
EFFECT
Friday, 7/19/2019
Notice of Effectiveness
CORRESP
Wednesday, 7/17/2019
A correspondence can be sent as a document with another submission type or can be sent as a separate submission.
EFFECT
Tuesday, 7/9/2019
Notice of Effectiveness
POS AM
Wednesday, 7/3/2019
Post-effective amendment to a registration statement that is not immediately effective upon filing
EFFECT
Friday, 5/31/2019
Notice of Effectiveness
CORRESP
Wednesday, 5/29/2019
A correspondence can be sent as a document with another submission type or can be sent as a separate submission.
D
Friday, 5/10/2019
Exempt (Private) Offering
CT ORDER
Monday, 7/2/2018
Order Granting Confidential Treatment
EFFECT
Wednesday, 6/27/2018
Notice of Effectiveness
CORRESP
Monday, 6/25/2018
A correspondence can be sent as a document with another submission type or can be sent as a separate submission.
CORRESP
Monday, 6/25/2018
A correspondence can be sent as a document with another submission type or can be sent as a separate submission.
CERT
Friday, 6/22/2018
Certification by an exchange approving securities for listing
8-A12B
Friday, 6/22/2018
Form for the registration / listing of a class of securities on a national securities exchange pursuant to Section 12(b)
CORRESP
Friday, 6/15/2018
A correspondence can be sent as a document with another submission type or can be sent as a separate submission.
CORRESP
Friday, 6/8/2018
A correspondence can be sent as a document with another submission type or can be sent as a separate submission.
CORRESP
Friday, 6/1/2018
A correspondence can be sent as a document with another submission type or can be sent as a separate submission.
D
Thursday, 1/5/2017
Exempt (Private) Offering
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Ownership (132)

SC 13D/A
Thursday, 9/16/2021
BAUPOST GROUP LLC/MA: Major Shareholders
4/A
Thursday, 9/16/2021
KLARMAN SETH A: Statement of changes in beneficial ownership of securities
4
Tuesday, 9/14/2021
Plenge Robert M: Statement of changes in beneficial ownership of securities
4
Tuesday, 9/14/2021
Demetri George: Statement of changes in beneficial ownership of securities
4
Tuesday, 9/14/2021
Smith Brendan: Statement of changes in beneficial ownership of securities
4
Tuesday, 9/14/2021
Meyer Robert J.: Statement of changes in beneficial ownership of securities
4
Tuesday, 9/14/2021
FORMELA JEAN FRANCOIS: Statement of changes in beneficial ownership of securities
4
Tuesday, 9/14/2021
Sanofi: Statement of changes in beneficial ownership of securities
4
Tuesday, 9/14/2021
Beckman Daniella: Statement of changes in beneficial ownership of securities
4
Tuesday, 9/14/2021
Hughes Owen: Statement of changes in beneficial ownership of securities
4
Tuesday, 9/14/2021
Renaud Ronald C JR: Statement of changes in beneficial ownership of securities
4/A
Tuesday, 9/14/2021
Renaud Ronald C JR: Statement of changes in beneficial ownership of securities
4
Tuesday, 9/14/2021
Sutherland Everett Rand: Statement of changes in beneficial ownership of securities
4
Tuesday, 9/14/2021
Burgess Paul D.: Statement of changes in beneficial ownership of securities
4
Tuesday, 9/14/2021
Demetri George: Statement of changes in beneficial ownership of securities
SC 13G/A
Friday, 9/10/2021
FMR LLC: Major Shareholders
SC 13D
Monday, 8/16/2021
Magnetar Financial LLC: Major Shareholders
SC 13D
Thursday, 8/12/2021
Sanofi: Major Shareholders
3
Thursday, 8/12/2021
Sanofi: Initial statement of beneficial ownership of securities
SC 13D/A
Wednesday, 8/4/2021
BAUPOST GROUP LLC/MA: Major Shareholders
4
Thursday, 6/17/2021
FORMELA JEAN FRANCOIS: Statement of changes in beneficial ownership of securities
4
Wednesday, 6/16/2021
Hughes Owen: Statement of changes in beneficial ownership of securities
4
Wednesday, 6/16/2021
Demetri George: Statement of changes in beneficial ownership of securities
4
Wednesday, 6/16/2021
Meyer Robert J.: Statement of changes in beneficial ownership of securities
4
Wednesday, 6/16/2021
Beckman Daniella: Statement of changes in beneficial ownership of securities
4
Wednesday, 6/16/2021
Plenge Robert M: Statement of changes in beneficial ownership of securities
SC 13G/A
Monday, 5/10/2021
FMR LLC: Major Shareholders
3
Tuesday, 4/20/2021
Smith Brendan: Initial statement of beneficial ownership of securities
4
Tuesday, 4/20/2021
Smith Brendan: Statement of changes in beneficial ownership of securities
4
Friday, 4/9/2021
Renaud Ronald C JR: Statement of changes in beneficial ownership of securities
4
Tuesday, 3/23/2021
Sutherland Everett Rand: Statement of changes in beneficial ownership of securities
3
Tuesday, 3/23/2021
Sutherland Everett Rand: Initial statement of beneficial ownership of securities
4
Tuesday, 3/9/2021
Burgess Paul D.: Statement of changes in beneficial ownership of securities
4
Tuesday, 3/9/2021
Barbier Ann: Statement of changes in beneficial ownership of securities
4
Tuesday, 3/9/2021
Wooster Richard: Statement of changes in beneficial ownership of securities
4
Tuesday, 3/9/2021
Renaud Ronald C JR: Statement of changes in beneficial ownership of securities
5
Tuesday, 2/16/2021
LYNCH DANIEL: Annual statement of changes in beneficial ownership of securities
SC 13G/A
Friday, 2/12/2021
RTW INVESTMENTS, LP: Major Shareholders
SC 13G/A
Monday, 2/8/2021
FMR LLC: Major Shareholders
SC 13G
Thursday, 2/4/2021
Sanofi: Major Shareholders
SC 13G/A
Tuesday, 2/2/2021
Atlas Venture Fund VIII, L.P.: Major Shareholders
SC 13G/A
Monday, 2/1/2021
BlackRock Inc.: Major Shareholders
SC 13G/A
Monday, 1/25/2021
TAKEDA PHARMACEUTICAL CO LTD: Major Shareholders
4
Thursday, 1/14/2021
Renaud Ronald C JR: Statement of changes in beneficial ownership of securities
4
Wednesday, 12/23/2020
FORMELA JEAN FRANCOIS: Statement of changes in beneficial ownership of securities
4
Wednesday, 11/18/2020
Renaud Ronald C JR: Statement of changes in beneficial ownership of securities
SC 13G/A
Tuesday, 11/10/2020
FMR LLC: Major Shareholders
4
Thursday, 8/27/2020
FORMELA JEAN FRANCOIS: Statement of changes in beneficial ownership of securities
SC 13D/A
Monday, 8/10/2020
BAUPOST GROUP LLC/MA: Major Shareholders
4
Tuesday, 6/30/2020
BAUPOST GROUP LLC/MA: Statement of changes in beneficial ownership of securities
4
Tuesday, 6/30/2020
Shire Human Genetic Therapies, Inc.: Statement of changes in beneficial ownership of securities
4
Wednesday, 6/17/2020
Beckman Daniella: Statement of changes in beneficial ownership of securities
4
Wednesday, 6/17/2020
LYNCH DANIEL: Statement of changes in beneficial ownership of securities
4
Wednesday, 6/17/2020
FORMELA JEAN FRANCOIS: Statement of changes in beneficial ownership of securities
4
Tuesday, 6/16/2020
Meyer Robert J.: Statement of changes in beneficial ownership of securities
4
Tuesday, 6/16/2020
Hughes Owen: Statement of changes in beneficial ownership of securities
4
Tuesday, 6/16/2020
Plenge Robert M: Statement of changes in beneficial ownership of securities
4
Tuesday, 6/16/2020
Demetri George: Statement of changes in beneficial ownership of securities
4
Friday, 6/5/2020
Shire Human Genetic Therapies, Inc.: Statement of changes in beneficial ownership of securities
4
Wednesday, 6/3/2020
TAKEDA PHARMACEUTICAL CO LTD: Statement of changes in beneficial ownership of securities
3
Wednesday, 6/3/2020
TAKEDA PHARMACEUTICAL CO LTD: Initial statement of beneficial ownership of securities
SC 13D/A
Monday, 5/11/2020
BAUPOST GROUP LLC/MA: Major Shareholders
4
Thursday, 3/5/2020
Renaud Ronald C JR: Statement of changes in beneficial ownership of securities
4
Thursday, 3/5/2020
Burgess Paul D.: Statement of changes in beneficial ownership of securities
4
Thursday, 3/5/2020
Schroer John R.: Statement of changes in beneficial ownership of securities
4
Thursday, 3/5/2020
Wooster Richard: Statement of changes in beneficial ownership of securities
4
Thursday, 3/5/2020
Barbier Ann: Statement of changes in beneficial ownership of securities
SC 13G
Friday, 2/14/2020
RTW INVESTMENTS, LP: Major Shareholders
SC 13D/A
Friday, 2/14/2020
GLAXOSMITHKLINE PLC: Major Shareholders
SC 13G/A
Friday, 2/14/2020
Omega Fund IV, L.P.: Major Shareholders
SC 13G/A
Friday, 2/7/2020
FMR LLC: Major Shareholders
SC 13G
Friday, 2/7/2020
BlackRock Inc.: Major Shareholders
SC 13G/A
Tuesday, 2/4/2020
Atlas Venture Fund VIII, L.P.: Major Shareholders
SC 13D
Friday, 9/20/2019
BAUPOST GROUP LLC/MA: Major Shareholders
3
Friday, 9/20/2019
KLARMAN SETH A: Initial statement of beneficial ownership of securities
SC 13G/A
Monday, 9/9/2019
BAUPOST GROUP LLC/MA: Major Shareholders
3
Monday, 7/15/2019
Demetri George: Initial statement of beneficial ownership of securities
4
Monday, 7/15/2019
Demetri George: Statement of changes in beneficial ownership of securities
4
Wednesday, 6/19/2019
Beckman Daniella: Statement of changes in beneficial ownership of securities
4
Wednesday, 6/19/2019
FORMELA JEAN FRANCOIS: Statement of changes in beneficial ownership of securities
3/A
Wednesday, 6/19/2019
FORMELA JEAN FRANCOIS: Initial statement of beneficial ownership of securities
4
Wednesday, 6/19/2019
LYNCH DANIEL: Statement of changes in beneficial ownership of securities
4
Wednesday, 6/19/2019
Hughes Owen: Statement of changes in beneficial ownership of securities
4
Wednesday, 6/19/2019
Plenge Robert M: Statement of changes in beneficial ownership of securities
4
Wednesday, 6/19/2019
Meyer Robert J.: Statement of changes in beneficial ownership of securities
SC 13D/A
Friday, 5/3/2019
GLAXOSMITHKLINE PLC: Major Shareholders
3
Friday, 4/26/2019
Wooster Richard: Initial statement of beneficial ownership of securities
4
Friday, 4/26/2019
Wooster Richard: Statement of changes in beneficial ownership of securities
3
Thursday, 4/11/2019
Plenge Robert M: Initial statement of beneficial ownership of securities
4
Thursday, 4/11/2019
Plenge Robert M: Statement of changes in beneficial ownership of securities
4
Tuesday, 3/12/2019
Heartlein Michael: Statement of changes in beneficial ownership of securities
4
Tuesday, 3/12/2019
Fenton Brian: Statement of changes in beneficial ownership of securities
4
Tuesday, 3/12/2019
Burgess Paul D.: Statement of changes in beneficial ownership of securities
4
Tuesday, 3/12/2019
Schroer John R.: Statement of changes in beneficial ownership of securities
4
Tuesday, 3/12/2019
Barbier Ann: Statement of changes in beneficial ownership of securities
4
Tuesday, 3/12/2019
Cloghessy Paula: Statement of changes in beneficial ownership of securities
4
Tuesday, 3/12/2019
Renaud Ronald C JR: Statement of changes in beneficial ownership of securities
SC 13G
Thursday, 2/14/2019
TAKEDA PHARMACEUTICAL CO LTD: Major Shareholders
SC 13G
Wednesday, 2/13/2019
Omega Fund IV, L.P.: Major Shareholders
SC 13G/A
Wednesday, 2/13/2019
FMR LLC: Major Shareholders
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Prospectus (35)

S-8 POS
Tuesday, 9/14/2021
Post-effective amendment to a S-8 registration statement
SC TO-T/A
Tuesday, 9/14/2021
Third party tender offer statement
S-8 POS
Tuesday, 9/14/2021
Post-effective amendment to a S-8 registration statement
S-8 POS
Tuesday, 9/14/2021
Post-effective amendment to a S-8 registration statement
S-8 POS
Tuesday, 9/14/2021
Post-effective amendment to a S-8 registration statement
SC TO-T/A
Friday, 8/27/2021
Third party tender offer statement
SC TO-T
Monday, 8/16/2021
Third party tender offer statement
SC TO-C
Tuesday, 8/3/2021
Written communication relating to an issuer or third party tender offer
S-8
Monday, 3/1/2021
Initial registration statement for securities to be offered to employees pursuant to employee benefit plans
S-3ASR
Monday, 8/17/2020
Automatic shelf registration statement of securities of well-known seasoned issuers
424B5
Friday, 6/26/2020
Prospectus filed pursuant to Rule 424(b)(5)
424B5
Wednesday, 6/24/2020
Prospectus filed pursuant to Rule 424(b)(5)
S-3ASR
Wednesday, 6/24/2020
Automatic shelf registration statement of securities of well-known seasoned issuers
S-3/A
Monday, 5/4/2020
Registration statement for specified transactions by certain issuers
S-8
Friday, 3/13/2020
Initial registration statement for securities to be offered to employees pursuant to employee benefit plans
S-3
Friday, 3/13/2020
Registration statement for specified transactions by certain issuers
424B5
Wednesday, 9/18/2019
Prospectus filed pursuant to Rule 424(b)(5)
424B5
Tuesday, 9/17/2019
Prospectus filed pursuant to Rule 424(b)(5)
424B3
Monday, 7/22/2019
Prospectus filed pursuant to Rule 424(b)(3)
424B3
Wednesday, 7/10/2019
Prospectus filed pursuant to Rule 424(b)(3)
S-3
Wednesday, 7/3/2019
Registration statement for specified transactions by certain issuers
424B3
Friday, 5/31/2019
Prospectus filed pursuant to Rule 424(b)(3)
S-1
Friday, 5/24/2019
General form of registration statement for all companies including face-amount certificate companies
S-8
Friday, 5/24/2019
Initial registration statement for securities to be offered to employees pursuant to employee benefit plans
S-8
Monday, 7/2/2018
Initial registration statement for securities to be offered to employees pursuant to employee benefit plans
424B4
Friday, 6/29/2018
Prospectus filed pursuant to Rule 424(b)(4)
S-1MEF
Wednesday, 6/27/2018
A new registration statement filed under Rule 462(b) to add securities to a prior related effective registration statement filed on Form S-1
S-1/A
Monday, 6/18/2018
General form of registration statement for all companies including face-amount certificate companies
S-1/A
Tuesday, 6/12/2018
General form of registration statement for all companies including face-amount certificate companies
S-1
Friday, 6/1/2018
General form of registration statement for all companies including face-amount certificate companies
DRS/A
Friday, 5/18/2018
Draft registration statement submitted by Emerging Growth Company under Securities Act Section 6(e) or by Foreign Private Issuer under Division of Corporation Finance policy
DRSLTR
Friday, 5/18/2018
Correspondence Related to Draft Registration Statement
DRS/A
Friday, 3/30/2018
Draft registration statement submitted by Emerging Growth Company under Securities Act Section 6(e) or by Foreign Private Issuer under Division of Corporation Finance policy
DRSLTR
Friday, 3/30/2018
Correspondence Related to Draft Registration Statement
DRS
Friday, 2/9/2018
Draft registration statement submitted by Emerging Growth Company under Securities Act Section 6(e) or by Foreign Private Issuer under Division of Corporation Finance policy
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Proxies (6)

DEF 14A
Monday, 4/19/2021
Definitive proxy statements
DEFA14A
Monday, 4/19/2021
Definitive additional proxy soliciting materials including Rule 14(a)(12) material. Note: Submission type DEFA14A can be filed as part of Form 8-K. For filers subject to 8-K filing requirements, we recommend the use of the 8-K combined form type as the easiest method for fulfilling your filing requirement for both forms.
DEF 14A
Wednesday, 4/22/2020
Definitive proxy statements
DEFA14A
Wednesday, 4/22/2020
Definitive additional proxy soliciting materials including Rule 14(a)(12) material. Note: Submission type DEFA14A can be filed as part of Form 8-K. For filers subject to 8-K filing requirements, we recommend the use of the 8-K combined form type as the easiest method for fulfilling your filing requirement for both forms.
DEF 14A
Thursday, 4/25/2019
Definitive proxy statements
DEFA14A
Thursday, 4/25/2019
Definitive additional proxy soliciting materials including Rule 14(a)(12) material. Note: Submission type DEFA14A can be filed as part of Form 8-K. For filers subject to 8-K filing requirements, we recommend the use of the 8-K combined form type as the easiest method for fulfilling your filing requirement for both forms.
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