Shire Acquisitions Investments Ireland DAC

Notice of suspension of duty to file reports pursuant to Section 13 and 15(d) of the Act

Post-effective Amendment to an automatic shelf registration statement on Form S-3ASR or Form F-3ASR

Notification filed by issuer to voluntarily withdraw a class of securities from listing and registration on a national securities exchange

None

Form for the registration / listing of a class of securities on a national securities exchange pursuant to Section 12(b)

Prospectus filed pursuant to Rule 424(b)(2)

Filing under Securities Act Rules 163/433 of free writing prospectuses

Prospectus filed pursuant to Rule 424(b)(5)

Automatic shelf registration statement of securities of well-known seasoned issuers