CONDENSED STATEMENT OF CHANGES IN STOCKHOLDERS' EQUITY - USD ($)
$ in Thousands
Total
Common Stock [Member]
Additional Paid-in Capital [Member]
Accumulated Deficit [Member]
Treasury Stock [Member]
Balance at Dec. 31, 2012 $ (5,887) $ 0 [1] $ 118,247 $ (124,112) $ (22)
Balance (in shares) at Dec. 31, 2012   604,195      
Net loss (27,450) $ 0 0 (27,450) 0
Stock based compensation 796 0 796 0 0
Compensation granted in common stock 94 $ 0 [1] 94 0 0
Compensation granted in common stock (in Shares)   1,525      
Conversion of 2011 Convertible Note Payable Principal Balance 15,000 $ 0 [1] 15,000 0 0
Conversion of 2011 Convertible Note Payable Principal Balance (in shares)   112,782      
Issuance of stock in exchange for payment of interest on convertible debt 180 $ 0 [1] 180 0 0
Issuance of stock in exchange for payment of interest on convertible debt (in shares)   4,168      
Issuance of stock for inducement of 2011 Convertible note payable 0 $ 0 [1] 0 0 0
Issuance of stock for inducement of 2011 Convertible note payable (in shares)   15,933      
Issuance of stock for conversion of Bridge Loan and extinguishment 11,480 $ 0 [1] 11,480 0 0
Issuance of stock for conversion of Bridge Loan and extinguishment (in shares)   218,753      
Issuance of Warrants - conversion of bridge loan 392 $ 0 392 0 0
Issuance of warrants for the Bridge Loan and extinguishment 401 0 401 0 0
Issuance of shares and warrants - IPO 6,751 $ 0 [1] 6,751 0 0
Issuance of shares and warrants - IPO (in shares)   133,780      
Issuance of shares and warrants - IPO over-allotment 1,027 $ 0 [1] 1,027 0 0
Issuance of shares and warrants - IPO over-allotment (in shares)   20,067      
Issuance of - shares, warrants, and modification of options for one-time agreement with MBTH 10,067 $ 0 [1] 10,067 0 0
Issuance of - shares, warrants, and modification of options for one-time agreement with MBTH (in shares)   159,946      
Issuance of shares and warrants - secondary offering 9,147 $ 0 [1] 9,147 0 0
Issuance of shares and warrants - secondary offering (in shares)   571,500      
Issuance of stock - secondary offering exercise of over-allotment 415 $ 0 [1] 415 0 0
Issuance of stock - secondary offering exercise of over-allotment (in shares)   25,500      
Issuance of stock from exercise of warrants 3 $ 0 [1] 3 0 0
Issuance of stock from exercise of warrants (in shares)   86      
Balance at Dec. 31, 2013 22,416 $ 0 [1] 174,000 (151,562) (22)
Balance (in shares) at Dec. 31, 2013   1,868,235      
Net loss (18,978) $ 0 0 (18,978) 0
Stock based compensation 625 0 625 0 0
Compensation granted in common stock 307 $ 0 [1] 307 0 0
Compensation granted in common stock (in Shares)   14,560      
Issuance of stock - 15 million purchase agreement 439 $ 0 [1] 439 0 0
Issuance of stock - 15 million purchase agreement (in shares)   27,500      
Issuance of stock as payment of 2011 and 2012 bonus 272 $ 0 [1] 272 0 0
Issuance of stock as payment of 2011 and 2012 bonus (in shares)   14,887      
Issuance of stock in exchange for payment of interest on convertible debt 180 $ 0 [1] 180 0 0
Issuance of stock in exchange for payment of interest on convertible debt (in shares)   8,466      
Issuance of stock - third offering 8,816 $ 0 [1] 8,816 0 0
Issuance of stock - third offering (in shares)   526,500      
Issuance of stock - 1 million purchase agreement 961 $ 0 [1] 961 0 0
Issuance of stock - 1 million purchase agreement (in shares)   50,000      
Issuance of stock - S-3 financing 1,302 $ 0 [1] 1,302 0 0
Issuance of stock - S-3 financing (in shares)   104,159      
Issuance of stock to financing agent - Series A financing 17 $ 0 [1] 17 0 0
Issuance of stock to financing agent - Series A financing (in shares)   3,315      
Balance at Dec. 31, 2014 16,357 $ 0 [1] 186,919 (170,540) (22)
Balance (in shares) at Dec. 31, 2014   2,617,622      
Net loss (10,555) $ 0 0 (10,555) 0
Stock based compensation 432 0 432 0 0
Compensation granted in common stock 1,542 $ 0 [1] 1,542 0 0
Compensation granted in common stock (in Shares)   956,634      
Issuance of common stock in settlement of due to related party (MBTH) 1,756 $ 0 [1] 1,756 0 0
Issuance of common stock in settlement of due to related party (MBTH) (in shares)   399,114      
Issuance of stock - 15 million purchase agreement (135) $ 0 [1] (135) 0 0
Issuance of stock - 15 million purchase agreement (in shares)   0      
Issuance of common stock in connection with Series A Preferred Stock conversion 1,011 $ 0 [1] 1,011 0 0
Issuance of common stock in connection with Series A Preferred Stock conversion (in shares)   239,247      
Issuance of common stock in connection with Series B Preferred Stock conversion (related parties) 1,003 $ 0 [1] 1,003 0 0
Issuance of common stock in connection with Series B Preferred Stock conversion (related parties) (in shares)   222,791      
Issuance of common stock in connection with Series B Preferred Stock conversion 474 $ 0 [1] 474 0 0
Issuance of common stock in connection with Series B Preferred Stock conversion (in shares)   182,708      
Issuance of common stock in connection with Series C Preferred Stock conversion 3,189 $ 0 [1] 3,189 0 0
Issuance of common stock in connection with Series C Preferred Stock conversion (in shares)   946,518      
Issuance of common stock in connection with settlement of amounts due to related parties 24 $ 0 [1] 24 0 0
Issuance of common stock in connection with settlement of amounts due to related parties (in shares)   5,310      
Issuance of common stock in connection with Series B Financing 10 $ 0 [1] 10 0 0
Issuance of common stock in connection with Series B Financing (in shares)   2,462      
Issuance of common stock in connection with Series C Financing 53 $ 0 [1] 53 0 0
Issuance of common stock in connection with Series C Financing (in shares)   11,864      
Issuance of common stock in connection with repayment of accrued interest 90 $ 0 [1] 90 0 0
Issuance of common stock in connection with repayment of accrued interest (in shares)   31,343      
Issuance of common stock in connection with underwritten offering, net of offering costs 1,302 $ 0 [1] 1,302 0 0
Issuance of common stock in connection with underwritten offering, net of offering costs (in shares)   2,550,000      
Issuance of common stock in connection with reclassification of derivative liability and warrant exercise 1,214 $ 0 [1] 1,214 0 0
Issuance of common stock in connection with reclassification of derivative liability and warrant exercise (in shares)   2,450,000      
Dividends and deemed dividends (3,079) $ 0 [1] (3,079)    
Issuance of stock to financing agent - Series A financing 5,677        
Balance at Sep. 30, 2015 $ 14,688 $ 0 [1] $ 195,805 $ (181,095) $ (22)
Balance (in shares) at Sep. 30, 2015   10,615,613      
[1] Less than $1