144 0001267487 XXXXXXXX LIVE 0001804591 23andMe Holding Co. 001-39587 349 OYSTER POINT BOULEVARD SOUTH SAN FRANCISCO CA 94080 (650) 938-6300 HIBBS KATHY L Officer Common Morgan Stanley Smith Barney LLC Executive Financial Services

1 New York Plaza New York NY 10004

38548 38362.97 304927539 09/21/2023 NASDAQ Common 09/21/2023 Exercise of Stock Options Issuer N 38548 09/21/2023 Cash N KATHY L HIBBS

349 Oyster Point Boulevard South San Francisco CA 94080

Common 09/07/2023 40896 43484.72 KATHY L HIBBS

349 Oyster Point Boulevard South San Francisco CA 94080

Common 08/24/2023 40894 43118.63 KATHY L HIBBS

349 Oyster Point Boulevard South San Francisco CA 94080

Common 08/15/2023 40894 53939.19 KATHY L HIBBS

349 Oyster Point Boulevard South San Francisco CA 94080

Common 07/27/2023 40894 77256.94 KATHY L HIBBS

349 Oyster Point Boulevard South San Francisco CA 94080

Common 07/13/2023 40894 74238.97 KATHY L HIBBS

349 Oyster Point Boulevard South San Francisco CA 94080

Common 06/29/2023 40894 70431.74 09/21/2023 03/09/2023 /s/ Kathy L Hibbs