X0306 4/A 2022-03-28 2022-03-30 0 0001537917 TYME TECHNOLOGIES, INC. TYME 0001711342 Hoffman Steve C/O TYME TECHNOLOGIES, INC. 1 PLUCKEMIN WAY, SUITE 103 BEDMINSTER NJ 07921 1 0 1 0 Common Stock 2022-03-28 4 S 0 78125 0.3427 D 21038191 D Common Stock 2022-03-29 4 S 0 78125 0.3559 D 20960066 D The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on June 17, 2021. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $0.33 to $0.3651, on March 28, 2022. The reporting person undertakes to provide to Tyme Technologies, Inc., any security holder of Tyme Technologies, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $0.3397 to $0.3631, on March 29, 2022. The reporting person undertakes to provide to Tyme Technologies, Inc., any security holder of Tyme Technologies, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote. Filed to correct prior filing, which incorrectly identified the reporting person as an officer of the issuer. /s/ Steve Hoffman 2022-04-01