Note 6 - Fair Value Measurement and Financial Instruments (Tables)
12 Months Ended
Dec. 31, 2014
Note 6 - Fair Value Measurement and Financial Instruments (Tables) [Line Items]  
Fair Value, Assets Measured on Recurring Basis [Table Text Block]
   

December 31,

2014

   

Level 1

   

Level 2

   

Level 3

 

Assets:

                               

Money market funds

  $ 99     $ 99     $     $  

Commercial paper

    12,398             12,398        

U.S. government sponsored enterprise securities

    6,308             6,308        

Corporate debt securities

    3,166             3,166        

Total assets

  $ 21,971     $ 99     $ 21,872     $  

Liabilities:

                               

Warrant liability

  $     $     $     $  

Stock-based compensation liability

    22                   22  

Total liabilities

  $ 22     $     $     $ 22  
   

December 31,

2013

   

Level 1

   

Level 2

   

Level 3

 

Assets:

                               

Money market funds

  $ 55     $ 55     $     $  

Commercial paper

    23,570             23,570        

U.S. government sponsored enterprise securities

    17,005             17,005        

Corporate debt securities

    6,507             6,507        

Total assets

  $ 47,137     $ 55     $ 47,082     $  

Liabilities:

                               

Warrant liability

  $ 883     $     $     $ 883  

Stock-based compensation liability

    202                   202  

Total liabilities

  $ 1,085     $     $     $ 1,085  
Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
   

For the Years Ended December 31,

 
   

2014

   

2013

   

2012

 

Expected Life of the Option Term (years)

    3.7       3.9       3.9  

Risk-free interest rate

    1.2 %     0.9 %     1.2 %

Dividend rate

    0 %     0 %     0 %

Volatility

    76.2 %     83.8 %     73.9 %

Forfeiture rate

    5.3 %     8.1 %     9.0 %
Warrant Liability [Member]  
Note 6 - Fair Value Measurement and Financial Instruments (Tables) [Line Items]  
Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
   

December 31,

 
   

2014

   

2013

 

Stock price at the end of each reporting period

  $ 0.54     $ 3.70  

Weighted average exercise price

  $ 29.14     $ 25.45  

Risk-free interest rate

    0.25

%

    0.62

%

Volatility

    425.17

%

    115.09

%

Dividend yield

    0.00

%

    0.00

%

Expected life in years

    0.21       2.51  

Calculated fair value per common share purchase warrant

  $     $ 0.96  
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
   

For the Years Ended December 31,

 
   

2014

   

2013

 

Liabilities:

               

Balance at beginning of period:

  $ 883     $  

Calculation of initial warrant liability fair value

          1,572  

Reclassification of fair value of warrant liability to equity as a result of the amendment to convert the exercise price of certain warrants from Canadian dollars to U.S. dollars of the underlying common share purchase warrants

    (834 )      

Change in fair value of warrant liability included in other expense, net

    (49 )     (689

)

Balance at end of period:

  $     $ 883  
Stock-based Compensation Liability [Member]  
Note 6 - Fair Value Measurement and Financial Instruments (Tables) [Line Items]  
Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
   

December 31,

 
   

2014

   

2013

 

Stock price at the end of each reporting period

  $ 0.54     $ 3.70  

Weighted average exercise price

  $ 15.83     $ 17.66  

Risk-free interest rate

    0.88

%

    1.00

%

Volatility

    138.38

%

    94.53

%

Dividend yield

    0.00

%

    0.00

%

Expected life in years

    2.49       3.42  

Calculated fair value per stock option

  $ 0.10     $ 1.17  
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
   

For the Years Ended December 31,

 
   

2014

   

2013

 

Liabilities:

               

Balance at beginning of period

  $ 202     $  

Calculation of initial stock-based compensation liability fair value

            163  

Change in fair value of stock-based compensation liability recorded as an adjustment to contributed surplus

    (180 )     39  

Balance at end of period:

  $ 22     $ 202