Cover - shares
3 Months Ended
Mar. 31, 2020
Apr. 30, 2020
Cover [Abstract]    
Document Type 10-Q/A  
Amendment Flag false  
Document Quarterly Report true  
Document Transition Report false  
Document Period End Date Mar. 31, 2020  
Document Fiscal Period Focus Q1  
Document Fiscal Year Focus 2020  
Current Fiscal Year End Date --12-31  
Entity File Number 001-38586  
Entity Registrant Name RUBIUS THERAPEUTICS, INC.  
Entity Central Index Key 0001709401  
Entity Tax Identification Number 46-2688109  
Entity Incorporation, State or Country Code DE  
Entity Address, Address Line One 399 Binney Street  
Entity Address, Address Line Two Suite 300  
Entity Address, City or Town Cambridge  
Entity Address, State or Province MA  
Entity Address, Postal Zip Code 02139  
City Area Code 617  
Local Phone Number 679-9600  
Title of 12(b) Security Common Stock, par value $0.001 per share  
Trading Symbol RUBY  
Security Exchange Name NASDAQ  
Entity Current Reporting Status Yes  
Entity Interactive Data Current Yes  
Entity Filer Category Accelerated Filer  
Entity Small Business true  
Entity Emerging Growth Company true  
Elected Not To Use the Extended Transition Period false  
Entity Shell Company false  
Entity Common Stock, Shares Outstanding   80,476,102