CONDENSED CONSOLIDATED STATEMENTS STOCKHOLDERS EQUITY - USD ($)
$ in Thousands
Common stock
Additional paid-in capital
Accumulated other comprehensive income
Accumulated deficit
Total
Balances at Beginning of period (in shares) at Dec. 31, 2020 81,053,651        
Balances at Beginning of period at Dec. 31, 2020 $ 81 $ 621,946 $ 4 $ (480,471) $ 141,560
Issuance of common stock from public offering, net of commissions, underwriting discounts and offering costs of $800 $ 7 187,193     187,200
Issuance of common stock from public offering, net of commissions, underwriting discounts and offering costs (in shares) 6,896,552        
Issuance of common stock upon exercise of stock options $ 1 5,907     5,908
Issuance of common stock upon exercise of stock options (in shares) 1,237,324        
Stock-based compensation expense   8,642     8,642
Unrealized gains (losses) on investments     3   3
Net loss       (42,330) (42,330)
Balances at End of period (in shares) at Mar. 31, 2021 89,187,527        
Balances at End of period at Mar. 31, 2021 $ 89 823,688 7 (522,801) 300,983
Balances at Beginning of period (in shares) at Dec. 31, 2020 81,053,651        
Balances at Beginning of period at Dec. 31, 2020 $ 81 621,946 4 (480,471) 141,560
Net loss         (196,500)
Balances at End of period (in shares) at Dec. 31, 2021 90,063,770        
Balances at End of period at Dec. 31, 2021 $ 90 855,710   (677,018) 178,782
Issuance of common stock upon exercise of stock options   76     76
Issuance of common stock upon exercise of stock options (in shares) 18,228        
Vesting of restricted stock units 104,628        
Stock-based compensation expense   8,260     8,260
Unrealized gains (losses) on investments     (57)   (57)
Net loss       (52,412) (52,412)
Balances at End of period (in shares) at Mar. 31, 2022 90,186,626        
Balances at End of period at Mar. 31, 2022 $ 90 $ 864,046 $ (57) $ (729,430) $ 134,649