CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($)
$ in Thousands
Common stock
Additional paid-in capital
Accumulated other comprehensive income
Accumulated deficit
Total
Balances at Beginning of period (in shares) at Dec. 31, 2019 80,016,245        
Balances at Beginning of period at Dec. 31, 2019 $ 80 $ 586,798 $ 75 $ (312,740) $ 274,213
Issuance of common stock upon exercise of stock options   486     486
Issuance of common stock upon exercise of stock options (in shares) 413,721        
Stock-based compensation expense   8,488     8,488
Unrealized gains (losses) on investments     456   456
Net loss       (48,486) (48,486)
Balances at End of period (in shares) at Mar. 31, 2020 80,429,966        
Balances at End of period at Mar. 31, 2020 $ 80 595,772 531 (361,226) 235,157
Balances at Beginning of period (in shares) at Dec. 31, 2019 80,016,245        
Balances at Beginning of period at Dec. 31, 2019 $ 80 586,798 75 (312,740) 274,213
Net loss         (127,192)
Balances at End of period (in shares) at Sep. 30, 2020 80,923,820        
Balances at End of period at Sep. 30, 2020 $ 81 612,934 32 (439,932) 173,115
Balances at Beginning of period (in shares) at Dec. 31, 2019 80,016,245        
Balances at Beginning of period at Dec. 31, 2019 $ 80 586,798 75 (312,740) 274,213
Net loss         (167,700)
Balances at End of period (in shares) at Dec. 31, 2020 81,053,651        
Balances at End of period at Dec. 31, 2020 $ 81 621,946 4 (480,471) 141,560
Balances at Beginning of period (in shares) at Mar. 31, 2020 80,429,966        
Balances at Beginning of period at Mar. 31, 2020 $ 80 595,772 531 (361,226) 235,157
Issuance of common stock upon exercise of stock options   256     256
Issuance of common stock upon exercise of stock options (in shares) 115,553        
Stock-based compensation expense   8,252     8,252
Unrealized gains (losses) on investments     (337)   (337)
Net loss       (37,854) (37,854)
Balances at End of period (in shares) at Jun. 30, 2020 80,545,519        
Balances at End of period at Jun. 30, 2020 $ 80 604,280 194 (399,080) 205,474
Issuance of common stock upon exercise of stock options $ 1 669     670
Issuance of common stock upon exercise of stock options (in shares) 378,301        
Stock-based compensation expense   7,985     7,985
Unrealized gains (losses) on investments     (162)   (162)
Net loss       (40,852) (40,852)
Balances at End of period (in shares) at Sep. 30, 2020 80,923,820        
Balances at End of period at Sep. 30, 2020 $ 81 612,934 32 (439,932) 173,115
Balances at Beginning of period (in shares) at Dec. 31, 2020 81,053,651        
Balances at Beginning of period at Dec. 31, 2020 $ 81 621,946 4 (480,471) 141,560
Issuance of common stock from public offering, net of commissions, underwriting discounts and offering costs of $800 $ 7 187,193     187,200
Issuance of common stock from public offering, net of commissions, underwriting discounts and offering costs (in shares) 6,896,552        
Issuance of common stock upon exercise of stock options $ 1 5,907     5,908
Issuance of common stock upon exercise of stock options (in shares) 1,237,324        
Stock-based compensation expense   8,642     8,642
Unrealized gains (losses) on investments     3   3
Net loss       (42,330) (42,330)
Balances at End of period (in shares) at Mar. 31, 2021 89,187,527        
Balances at End of period at Mar. 31, 2021 $ 89 823,688 7 (522,801) 300,983
Balances at Beginning of period (in shares) at Dec. 31, 2020 81,053,651        
Balances at Beginning of period at Dec. 31, 2020 $ 81 621,946 4 (480,471) 141,560
Net loss         (141,526)
Balances at End of period (in shares) at Sep. 30, 2021 89,862,482        
Balances at End of period at Sep. 30, 2021 $ 90 846,112   (621,997) 224,205
Balances at Beginning of period (in shares) at Mar. 31, 2021 89,187,527        
Balances at Beginning of period at Mar. 31, 2021 $ 89 823,688 7 (522,801) 300,983
Issuance of common stock upon exercise of stock options $ 1 3,719     3,720
Issuance of common stock upon exercise of stock options (in shares) 532,400        
Stock-based compensation expense   9,597     9,597
Unrealized gains (losses) on investments     (6)   (6)
Net loss       (50,180) (50,180)
Balances at End of period (in shares) at Jun. 30, 2021 89,719,927        
Balances at End of period at Jun. 30, 2021 $ 90 837,004 1 (572,981) 264,114
Issuance of common stock upon exercise of stock options   919     919
Issuance of common stock upon exercise of stock options (in shares) 142,555        
Stock-based compensation expense   8,189     8,189
Unrealized gains (losses) on investments     $ (1)   (1)
Net loss       (49,016) (49,016)
Balances at End of period (in shares) at Sep. 30, 2021 89,862,482        
Balances at End of period at Sep. 30, 2021 $ 90 $ 846,112   $ (621,997) $ 224,205