Income Taxes (Tables)
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12 Months Ended |
Dec. 31, 2018 |
| Income Taxes |
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| Schedule of reconciliation of the U.S. federal statutory income tax rate to the Company’s effective income tax |
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Year ended
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December 31,
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2018
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2017
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|
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Federal statutory income tax rate
|
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(21.0)
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%
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(34.0)
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%
|
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State taxes, net of federal benefit
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(4.8)
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(3.2)
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Federal and state research and development tax credits
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(2.9)
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(1.4)
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Stock‑based compensation expense
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4.5
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12.8
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Other
|
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0.5
|
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0.7
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Remeasurement of deferred taxes due to the Tax Cuts and Jobs Act
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—
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11.1
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Increase in deferred tax asset valuation allowance
|
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23.7
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14.0
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Effective income tax rate
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—
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%
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—
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%
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| Summary of changes in the valuation allowance for deferred tax assets |
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December 31,
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2018
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2017
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Deferred tax assets:
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|
|
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|
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Net operating loss carryforwards
|
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$
|
25,508
|
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$
|
10,422
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Research and development tax credit carryforwards
|
|
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3,824
|
|
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1,241
|
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Accrued expenses
|
|
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1,139
|
|
|
413
|
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Capitalized intellectual property costs
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|
|
764
|
|
|
367
|
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Capitalized research and development expense
|
|
|
120
|
|
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131
|
|
Stock‑based compensation expense
|
|
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2,652
|
|
|
375
|
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Total deferred tax assets
|
|
|
34,007
|
|
|
12,949
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Deferred tax liabilities:
|
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|
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Depreciation and other
|
|
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(341)
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|
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(374)
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Total deferred tax liabilities
|
|
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(341)
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|
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(374)
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Valuation allowance
|
|
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(33,666)
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|
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(12,575)
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Net deferred tax assets
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$
|
—
|
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$
|
—
|
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| Net deferred tax assets |
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Year ended
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December 31,
|
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2018
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2017
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Valuation allowance as of beginning of year
|
|
$
|
12,575
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$
|
6,454
|
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Decreases recorded as benefit to income tax provision
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|
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—
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(4,887)
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Increases recorded to income tax provision
|
|
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21,091
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|
|
11,008
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Valuation allowance as of end of year
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$
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33,666
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$
|
12,575
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