Income Taxes (Tables)
12 Months Ended
Dec. 31, 2014
Income Taxes  
Schedule of reconciliation of income taxes computed using the U.S. federal statutory rate to that reflected in operations

        A reconciliation of income taxes computed using the U.S. federal statutory rate to that reflected in operations follows (in thousands):

                                                                                                                                                                                    

 

 

Year Ended December 31,

 

 

 

2014

 

2013

 

2012

 

Income tax benefit using U.S. federal statutory rate

 

$

(21,243

)

$

(20,635

)

$

(23,504

)

State income taxes, net of federal benefit

 

 

(2,494

)

 

(2,255

)

 

(2,774

)

Stock-based compensation

 

 

149

 

 

92

 

 

72

 

Research and development tax credits

 

 

(499

)

 

(1,277

)

 

(55

)

Change in the valuation allowance

 

 

23,186

 

 

27,194

 

 

25,175

 

Permanent items

 

 

910

 

 

(3,085

)

 

709

 

Other

 

 

(9

)

 

(34

)

 

377

 

​  

​  

​  

​  

​  

​  

 

 

$

 

$

 

$

—  

 

​  

​  

​  

​  

​  

​  

​  

​  

​  

​  

​  

​  

​  

 

Schedule of principal components of the Company's deferred tax assets

        The principal components of the Company's deferred tax assets are as follows (in thousands):

                                                                                                                                                                                    

 

 

December 31,

 

 

 

2014

 

2013

 

Current assets:

 

 

 

 

 

 

 

Accrued expenses

 

$

671

 

$

351

 

Deferred rent

 

 

 

 

9

 

​  

​  

​  

​  

Gross current deferred tax assets

 

 

671

 

 

360

 

​  

​  

​  

​  

Valuation allowance

 

 

(671

)

 

(360

)

​  

​  

​  

​  

Net current deferred tax assets

 

$

 

$

—  

 

​  

​  

​  

​  

​  

​  

​  

​  

​  

Non-current assets:

 

 

 

 

 

 

 

Net operating loss carryforwards

 

$

121,278

 

$

100,284

 

Capitalized research and development

 

 

356

 

 

662

 

Research and development credits

 

 

4,844

 

 

4,345

 

Depreciation and amortization

 

 

(47

)

 

110

 

Other

 

 

3,158

 

 

1,313

 

​  

​  

​  

​  

Gross non-current deferred tax assets

 

 

129,589

 

 

106,714

 

Valuation allowance

 

 

(129,589

)

 

(106,714

)

​  

​  

​  

​  

Net non-current deferred tax assets

 

$

 

$

—  

 

​  

​  

​  

​  

​  

​  

​  

​  

​