Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Operating activities    
Net loss $ (21,742) $ (19,447)
Adjustments to reconcile net loss to net cash used in operating activities:    
Net income from discontinued operations 0 (219)
Depreciation 34 23
Amortization of intangibles 0 123
Stock-based compensation 3,168 2,860
Amortization of premium on marketable securities 40 321
Amortization of debt discount 144 31
Changes in operating assets and liabilities:    
Prepaid expenses and other assets (97) 354
Accounts payable 1,354 73
Accrued and other liabilities 244 531
Net cash used in continuing operating activities (16,855) (15,131)
Net cash provided by discontinued operating activities 0 219
Net cash used in continuing operating activities (16,855) (15,350)
Investing activities    
Purchases of property and equipment (3) (71)
Purchases of marketable securities (7,004) (23,320)
Proceeds from maturities of marketable securities 11,134 38,952
Deposits on equipment 0 (18)
Net cash provided by investing activities 4,127 15,543
Financing activities    
Proceeds from sale of common stock, net of underwriting discounts and issuance cost 5,996 2,480
Proceeds from notes payable, net 0 9,748
Proceeds from exercise of common stock options 26 0
Net cash provided by financing activities 6,022 12,228
Net (decrease) increase in cash and cash equivalents (6,706) 12,640
Cash and cash equivalents—beginning of period 35,921 10,127
Cash and cash equivalents—end of period 29,215 22,767
Supplemental disclosures of cash flow information    
Cash paid for interest 621 71
Supplemental schedule of noncash investing and financing activities    
Fair value of warrants issued in connection with notes payable 0 317
Issuance costs related to at the market equity program in accounts payable and accrued expenses 0 23
Unrealized gain on investments $ 4 $ 30