Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Sep. 30, 2016
Sep. 30, 2015
Income Statement [Abstract]        
Royalty revenue $ 38 $ 35 $ 97 $ 109
Operating expenses:        
Research and development 4,283 4,235 12,939 12,050
General and administrative 2,618 2,372 8,142 7,460
Amortization of intangibles 0 41 0 123
Total operating expenses 6,901 6,648 21,081 19,633
Other (expense) income:        
Interest and other income 20 23 83 71
Interest and other expense (282) (203) (841) (213)
Other (expense) income, net (262) (180) (758) (142)
Net loss from continuing operations (7,125) (6,793) (21,742) (19,666)
Net income from discontinued operations (See Note 8) 0 219 0 219
Net loss $ (7,125) $ (6,574) $ (21,742) $ (19,447)
Net loss per share:        
Net loss per share from continuing operations, basic and diluted (in usd per share) $ (0.32) $ (0.34) $ (1.01) $ (0.99)
Net income per share from discontinued operations, basic and diluted (in usd per share) 0.00 0.01 0.00 0.01
Net loss per share, basic and diluted (in usd per share) $ (0.32) $ (0.33) $ (1.01) $ (0.98)
Weighted average number of shares used to compute net loss per share of common stock, basic and diluted (in shares) 22,096,610 20,183,939 21,532,953 19,902,815
Comprehensive loss:        
Net loss $ (7,125) $ (6,574) $ (21,742) $ (19,447)
Unrealized (loss) gain on investments (1) 4 4 30
Comprehensive loss $ (7,126) $ (6,570) $ (21,738) $ (19,417)