Commitments and Contingencies (Details Narrative)
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1 Months Ended |
6 Months Ended |
12 Months Ended |
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Dec. 17, 2021
USD ($)
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Nov. 30, 2021
USD ($)
ft²
m²
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Nov. 30, 2021
ILS (₪)
ft²
m²
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Nov. 01, 2021
USD ($)
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Nov. 01, 2021
ILS (₪)
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Sep. 11, 2020
USD ($)
ft²
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May 06, 2020
USD ($)
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May 06, 2020
GBP (£)
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Jan. 28, 2019
USD ($)
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Jan. 28, 2019
ILS (₪)
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Jan. 05, 2019
USD ($)
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Apr. 02, 2018
USD ($)
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Apr. 02, 2018
ILS (₪)
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Jan. 28, 2018
ft²
m²
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Jan. 31, 2022
USD ($)
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Apr. 30, 2021
GBP (£)
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Feb. 28, 2021
USD ($)
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Jan. 31, 2021
GBP (£)
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Nov. 30, 2020
USD ($)
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Sep. 30, 2020
GBP (£)
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Feb. 29, 2020
USD ($)
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Jan. 31, 2020
USD ($)
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Aug. 31, 2019
USD ($)
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May 31, 2019
ft²
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Jan. 31, 2019
USD ($)
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Dec. 31, 2015
ft²
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Sep. 30, 2020
USD ($)
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Dec. 31, 2021
USD ($)
ft²
m²
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Dec. 31, 2019
USD ($)
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Dec. 31, 2021
ILS (₪)
ft²
m²
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Aug. 01, 2020
USD ($)
ft²
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Apr. 30, 2020
USD ($)
ft²
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Feb. 02, 2020
USD ($)
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Jan. 24, 2019
USD ($)
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Dec. 31, 2018
USD ($)
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| Loss Contingencies [Line Items] |
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| Advance upfront payment |
$ 50,000,000.0
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| Additional payment received for development |
$ 620,000,000.0
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| Percentage of grants awarded expenditures |
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50.00%
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| Percentage of upfront payment |
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24.30%
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| Access fees payable |
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$ 2,500,000
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| Minimum [Member] |
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| Loss Contingencies [Line Items] |
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| Minimum annual maintenance fees |
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$ 30,000
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| Subsequent Event [Member] |
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| Loss Contingencies [Line Items] |
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| Advance upfront payment |
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$ 12,100,000
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| Second Amended and Restated License Agreement [Member] |
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| Loss Contingencies [Line Items] |
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| Description of sublicensing fees |
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sublicensing fee of 21.5% of the upfront payment (subject to certain reductions) and any milestone payments, and up to 50%
of all royalty payments (subject to a maximum payment of 5% of net sales of products)
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| ITI Collaboration Agreement [Member] |
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| Loss Contingencies [Line Items] |
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| Budgetary commitment amount |
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$ 2,200,000
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| GBP [Member] | License Agreement [Member] |
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| Loss Contingencies [Line Items] |
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| Agreed signature fee amount |
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$ 1,600,000
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£ 1,250,000
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£ 250,000
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£ 500,000
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£ 500,000
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| Clinical regulatory milestone | £ |
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8,000,000
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| Sales related milestones | £ |
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£ 22,500,000
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| Cell Cure [Member] |
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| Loss Contingencies [Line Items] |
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| Rentable area | ft² |
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1,432
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1,432
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10,054
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| Lease area | m² |
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133
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133
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934
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| Lease, renewal term |
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one five year and one approximate
three-year extension options
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one five year and one approximate
three-year extension options
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two five-year extension
options
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| Base rent and construction allowance per month |
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$ 3,757
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$ 3,951
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$ 26,000
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| Cell Cure [Member] | NIS [Member] |
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| Loss Contingencies [Line Items] |
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| Base rent and construction allowance per month | ₪ |
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₪ 11,880
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₪ 12,494
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₪ 93,827
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| Office space in New York City [Member] |
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| Loss Contingencies [Line Items] |
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| Rentable area | ft² |
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900
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900
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| Base rent |
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$ 5,050
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| Industrial Microbes, Inc [Member] | Alameda Sublease [Member] |
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| Loss Contingencies [Line Items] |
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| Base rent |
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$ 28,000
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| Base rent increase rate |
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3.00%
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| Lease area | ft² |
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10,000
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| IIA Cap [Member] |
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| Loss Contingencies [Line Items] |
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| Commitment amount |
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102,700,000
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| Roche [Member] | Subsequent Event [Member] |
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| Loss Contingencies [Line Items] |
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| Advance upfront payment |
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50,000,000.0
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| Hadasit [Member] | Subsequent Event [Member] |
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| Loss Contingencies [Line Items] |
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| Advance upfront payment |
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8,900,000
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| [custom:ReducedPaymentCommitmentAmount] |
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1,900,000
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| Budgetary commitment amount |
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$ 8,600,000
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| Other Commitments, Description |
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Lineage
is required to pay Hadasit 21.5% of any portion of the commitment not incurred within five years after the execution of the Agreement
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| Orbit Biomedical Limited [Member] | Research and Option Agreement [Member] |
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| Loss Contingencies [Line Items] |
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| Access fees payable |
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$ 2,500,000
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| Access fees |
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$ 1,250,000
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$ 1,250,000
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| Gyroscope Therapeutics Limited [Member] | Second Amendment [Member] |
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| Loss Contingencies [Line Items] |
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| Agreed signature fee amount |
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$ 500,000
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| Extension fees |
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$ 300,000
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| Gyroscope Therapeutics Limited [Member] | Third Amendment [Member] |
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Loss Contingencies [Line Items] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Agreed signature fee amount |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
$ 500,000
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Gyroscope Therapeutics Limited [Member] | Upon Signing [Member] | Second Amendment [Member] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Loss Contingencies [Line Items] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Extension fees |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
$ 200,000
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Future Years [Member] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Loss Contingencies [Line Items] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Minimum annual maintenance fees |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
60,000
|
|
|
|
|
|
|
|
| Carlsbad Lease [Member] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Loss Contingencies [Line Items] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Rentable area | ft² |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
8,841
|
|
|
|
|
|
|
|
|
|
|
|
| Lease commencement date |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Aug. 01, 2019
|
|
|
|
|
|
|
|
|
|
|
|
| Base rent |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
$ 23,959
|
|
|
|
|
| Base rent increase rate |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3.00%
|
|
|
|
|
| Lease expiration date |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Aug. 01, 2022
|
|
|
|
|
|
|
|
|
|
|
|
| Security deposit |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
$ 17,850
|
|
|
|
|
| Carlsbad Lease [Member] | First Twenty-Four Months [Member] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Loss Contingencies [Line Items] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Rentable area | ft² |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
7,000
|
|
|
|
|
| Merger Agreement [Member] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Loss Contingencies [Line Items] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Base rent |
|
|
|
|
|
$ 14,592
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
$ 72,676
|
|
|
| Base rent increase rate |
|
|
|
|
|
3.00%
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3.00%
|
|
|
| Security deposit |
|
|
|
|
|
$ 16,000
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
$ 424,000
|
|
|
| Number of buildings for lease |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
two buildings
|
|
|
|
|
|
|
|
|
|
| Security deposit reduction in value |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
$ 78,000
|
|
| Termination fees |
|
|
|
|
|
130,000
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Reduction of contractual obligations |
|
|
|
|
|
$ 780,000
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Thousand Ten Atlantic Premises [Member] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Loss Contingencies [Line Items] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Rentable area | ft² |
|
|
|
|
|
2,432
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
22,303
|
|
|
|
|
|
|
|
|
|
| Lease commencement date |
|
|
|
|
|
Oct. 01, 2020
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Lease expiration date |
|
|
|
|
|
Jan. 31, 2023
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Thousand Twenty Atlantic Premises [Member] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Loss Contingencies [Line Items] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Rentable area | ft² |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
8,492
|
|
|
|
|
|
|
|
|
|
| Industrial Microbes Sublease [Member] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Loss Contingencies [Line Items] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Security deposit |
|
|
|
|
|
$ 56,000
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Termination fees |
|
|
|
|
|
$ 30,000
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Rental income received |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
$ 119,000
|
|
|
|
|
|
|
|
|
| Proceeds from Construction in Progress |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Loss Contingencies [Line Items] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Construction allowances of leasehold improvements |
|
|
|
|
|
|
|
|
|
|
|
$ 1,100,000
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Proceeds from Construction in Progress | NIS [Member] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Loss Contingencies [Line Items] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Base rent | ₪ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
₪ 39,776
|
|
|
|
|
|
| Construction allowances of leasehold improvements | ₪ |
|
|
|
|
|
|
|
|
|
|
|
|
₪ 4,000,000
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Proceeds from Construction in Progress | December 31, 2018 Exchange Rate [Member] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Loss Contingencies [Line Items] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Base rent |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
$ 12,200
|
|
|
|
|
|
|
|
| Proceeds from Construction in Progress | Cell Cure [Member] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Loss Contingencies [Line Items] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Rentable area | ft² |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
7,842
|
|
7,842
|
|
|
|
|
|
| Lease expiration date |
|
Dec. 31, 2025
|
Dec. 31, 2025
|
|
|
|
|
|
|
|
|
|
|
Dec. 31, 2025
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Dec. 31, 2025
|
|
|
|
|
|
|
|
| Lease area | m² |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
728.5
|
|
728.5
|
|
|
|
|
|
| Lease, renewal term |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
option to extend the lease for five years
|
|
|
|
|
|
|
|
| January 2018 Lease [Member] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Loss Contingencies [Line Items] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Deposit |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
$ 420,000
|