Warrants (Tables)
 3 Months Ended
Feb. 29, 2020
Warrants [Abstract]  
Schedule of stockholders' equity note, warrants or rights
       Number         Shares issuable 
Warrant Exercise price    outstanding     Expiry     upon exercise 
               
June 2016 Warrants  $        19.30         277,478   June 02, 2021           138,739
October 2017 Warrants  $        12.50         181,818   October 13, 2020           181,818
October 2017 Placement              
   Agent Warrants  $        13.75          18,181   October 13, 2020            18,181
March 2018 Warrants  $          6.00         291,666   March 16, 2021           291,666
March 2018 Warrants  $          6.00         150,000   March 21, 2021           150,000
March 2018 Placement              
   Agent Warrants  $          7.50          29,166   March 16, 2021            29,166
March 2018 Placement              
   Agent Warrants  $          7.50          15,000   March 21, 2021            15,000
2018 Firm Warrants  $          0.75    20,000,000   October 16, 2023      20,000,000
October 2018 Placement              
   Agent Warrants  $      0.9375      1,160,314   October 16, 2023        1,160,314
       22,123,623            21,984,884
Schedule of warrant transactions
    Outstanding,  December 1,     2019 Issued Expired Exercised Outstanding,  February 29,  2020
June 2016 Warrants                    277,478                     -                   -                         -                    277,478
October 2017 Warrants                    181,818                     -                   -                         -                    181,818
October 2017 Placement          
   Agent Warrants                      18,181                     -                   -                         -                       18,181
March 2018 Warrants                    441,666                     -                   -                         -                    441,666
March 2018 Placement           
  Agent Warrants                      44,166                     -                   -                         -                       44,166
2018 Firm Warrants              20,000,000                     -                   -                         -               20,000,000
2018 Pre-Funded Warrants                 1,616,667                     -                   -         (1,616,667)                             -   
October 2018 Placement          
  Agent Warrants                 1,160,314                     -                   -                         -                 1,160,314
                 23,740,290                     -                   -         (1,616,667)            22,123,623

 

    Outstanding,  December 1, 2018 Issued Expired Exercised Outstanding,  February 28, 2019
June 2016 Warrants               277,478               -               -                   -                      277,478
October 2017 Warrants               181,818               -               -                   -                      181,818
October 2017 Placement          
   Agent Warrants                18,181               -               -                   -                        18,181
March 2018 Warrants               441,666               -               -                   -                      441,666
March 2018 Placement           
  Agent Warrants                44,166               -               -                   -                        44,166
2018 Firm Warrants          20,000,000               -               -                   -                  20,000,000
2018 Pre-Funded Warrants            4,410,001               -               -       (2,643,334)                1,766,667
October 2018 Placement          
  Agent Warrants            1,160,314               -               -                   -                   1,160,314
             26,533,624               -               -       (2,643,334)               23,890,290