| Schedule of stockholders' equity note, warrants or rights |
| | Exercise | | | Number | | | | | Shares issuable upon | | Warrant | | price ($) | | | outstanding | | | Expiry | | exercise | | | | | | | | | | | | | | 2018 Firm Warrants | | | 0.75 | | | | 20,000,000 | | | October 16, 2023 | | | 20,000,000 | | October 2018 Placement Agent Warrants | | | 0.9375 | | | | 1,160,314 | | | October 16, 2023 | | | 1,160,314 | | | | | | | | | 21,160,314 | | | | | | 21,160,314 | |
|
| Schedule of warrant transactions |
| | Outstanding, December 1, 2020 | | | Issued | | | Expired | | | Exercised | | | Outstanding, November 30, 2021 | | June 2016 Warrants | | | 277,478 | | | | - | | | | (277,478 | ) | | | - | | | | - | | March 2018 Warrants | | | 441,666 | | | | - | | | | (441,666 | ) | | | - | | | | - | | March 2018 Placement Agent Warrants | | | 44,166 | | | | - | | | | (44,166 | ) | | | - | | | | - | | 2018 Firm Warrants | | | 20,000,000 | | | | - | | | | - | | | | - | | | | 20,000,000 | | October 2018 Placement Agent Warrants | | | 1,160,314 | | | | - | | | | - | | | | - | | | | 1,160,314 | | | | | 21,923,624 | | | | - | | | | (763,310 | ) | | | - | | | | 21,160,314 | |
| | Outstanding, December 1, 2019 | | | Issued | | | Expired | | | Exercised | | | Outstanding, November 30, 2020 | | June 2016 Warrants | | | 277,478 | | | | - | | | | - | | | | - | | | | 277,478 | | October 2017 Warrants | | | 181,818 | | | | - | | | | (181,818 | ) | | | - | | | | - | | October 2017 Placement Agent Warrants | | | 18,181 | | | | - | | | | (18,181 | ) | | | - | | | | - | | March 2018 Warrants | | | 441,666 | | | | - | | | | - | | | | - | | | | 441,666 | | March 2018 Placement Agent Warrants | | | 44,166 | | | | - | | | | - | | | | - | | | | 44,166 | | 2018 Firm Warrants | | | 20,000,000 | | | | - | | | | - | | | | - | | | | 20,000,000 | | 2018 Pre-Funded Warrants | | | 1,616,667 | | | | - | | | | - | | | | (1,616,667 | ) | | | - | | October 2018 Placement Agent Warrants | | | 1,160,314 | | | | - | | | | - | | | | - | | | | 1,160,314 | | | | | 23,740,290 | | | | - | | | | (199,999 | ) | | | (1,616,667 | ) | | | 21,923,624 | |
|