Statement of Operations (USD $)
In Thousands, except Share data, unless otherwise specified
 12 Months Ended
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Revenues:      
Product sales $ 7,998 $ 5,178 $ 1,460
Collaborations, partnerships and other revenues 3,886 1,404 1,137
Total revenues 11,884 6,582 2,597
Costs and expenses:      
Cost of product sales 2,302 2,089 727
Research and development 16,622 14,301 13,660
Sales and marketing 6,516 4,398 3,031
General and administrative 10,707 8,024 6,482
Total costs and expenses 36,147 28,812 23,900
Loss from operations (24,263) (22,230) (21,303)
Other (expense) income:      
Interest expense (716) (34) (44)
Other income 21 0 3
Total other expense (695) (34) (41)
Net loss $ (24,958) $ (22,264) $ (21,344)
Net loss per share of common stock, basic and diluted $ (3.17) $ (12.89) $ (12.47)
Weighted average number of shares used in computing net loss per share of common stock, basic and diluted 7,878,060 1,727,086 1,711,567