Property and Equipment, Net
 12 Months Ended
Dec. 31, 2021
Property Plant And Equipment [Abstract]  
Property and Equipment, Net

5. Property and Equipment, Net

Property and equipment and related accumulated depreciation and amortization are as follows (in thousands):

 

 

 

December 31,

 

 

 

2021

 

 

2020

 

Computer equipment and software

 

$

987

 

 

$

971

 

Furniture and fixtures

 

 

2,113

 

 

 

2,054

 

Laboratory equipment

 

 

24,679

 

 

 

22,213

 

Leasehold improvements

 

 

14,128

 

 

 

13,726

 

 

 

 

41,907

 

 

 

38,964

 

Less accumulated depreciation and amortization

 

 

(22,276

)

 

 

(16,925

)

Construction-in-progress

 

 

1,991

 

 

 

66

 

Total property and equipment, net

 

$

21,622

 

 

$

22,105

 

Depreciation and amortization expense was $6.3 million, $6.6 million, and $4.7 million for the years ended December 31, 2021, 2020 and 2019, respectively.