Note 10 - Grants and Collaboration Revenue (Details Textual) - USD ($) |
12 Months Ended | |
|---|---|---|
Dec. 31, 2021 |
Dec. 31, 2020 |
|
| Revenue from Contract with Customer, Including Assessed Tax | $ 385,501 | $ 1,823,658 |
| Unused Grant Funds | 81,526 | |
| NIH Grants [Member] | ||
| Revenue from Contract with Customer, Including Assessed Tax | $ 385,501 | 1,438,465 |
| Research Agreements [Member] | ||
| Revenue from Contract with Customer, Including Assessed Tax | $ 385,193 | |