Note 9 - Income Taxes - Reconciliation of Income Tax Benefit (Details) - USD ($) |
12 Months Ended | |
|---|---|---|
Dec. 31, 2021 |
Dec. 31, 2020 |
|
| U.S. federal statutory rate applied to pretax loss | $ (3,899,767) | $ (621,194) |
| Permanent differences | 65 | |
| Research and development credits | (377,183) | (66,574) |
| Change in valuation allowance, net of expired items and other adjustments | 4,276,950 | 687,703 |
| Reported income tax expense | $ 0 | $ 0 |