Note 2 - Summary of Significant Accounting Policies (Details Textual) |
12 Months Ended | |||
|---|---|---|---|---|
Sep. 25, 2020 |
Jan. 21, 2020 |
Dec. 31, 2021
USD ($)
shares
|
Dec. 31, 2020
USD ($)
shares
|
|
| Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount (in shares) | shares | 213,831 | 1,001,948 | ||
| Research and Development Expense, Total | $ 15,554,171 | $ 2,444,459 | ||
| Upfront Fees for COH and PNP License[Member] | ||||
| Research and Development Expense, Total | $ 10,513,825 | |||
| Minimum [Member] | ||||
| Property, Plant and Equipment, Useful Life (Year) | 3 years | |||
| Maximum [Member] | ||||
| Property, Plant and Equipment, Useful Life (Year) | 5 years | |||
| Reverse Stock Split [Member] | ||||
| Stockholders' Equity Note, Stock Split, Conversion Ratio | 20 | 2,000 | ||