| Schedule of Accrued Liabilities [Table Text Block] |
| | | 2021 | | | 2020 | | | Accrued license fees – current | | $ | 3,000,000 | | | $ | - | | | Accrued license fees – noncurrent | | | 2,000,000 | | | | - | | | Accrued payroll | | | 269,000 | | | | 279,696 | | | Other accrued expenses | | | 108,826 | | | | 79,585 | | | Total accrued expenses | | $ | 5,377,826 | | | $ | 359,281 | | |