144 0001802649 XXXXXXXX LIVE 0001703647 Frequency Therapeutics, Inc. 001-39062 75 HAYDEN AVENUE SUITE 300 LEXINGTON MA 02421 781-315-4600 Arnold Wendy S Former Chief People Officer Common Fidelity Brokerage Services LLC

900 Salem Street Smithfield RI 02917

1696 1036.76 35751956 07/21/2023 NASDAQ Common 07/20/2023 Restricted Stock Vesting Issuer N 1696 07/20/2023 Compensation N Wendy Arnold

75 Hayden Avenue Suite 300 Lexington MA 02421

Common 07/06/2023 1767 597.42 Wendy Arnold

75 Hayden Avenue Suite 300 Lexington MA 02421

Common 07/07/2023 1669 595.17 Wendy Arnold

75 Hayden Avenue Suite 300 Lexington MA 02421

Common 07/10/2023 1655 619.96 Wendy Arnold

75 Hayden Avenue Suite 300 Lexington MA 02421

Common 07/11/2023 1733 645.54 Wendy Arnold

75 Hayden Avenue Suite 300 Lexington MA 02421

Common 07/12/2023 1671 662.72 Wendy Arnold

75 Hayden Avenue Suite 300 Lexington MA 02421

Common 07/13/2023 1686 663.10 Wendy Arnold

75 Hayden Avenue Suite 300 Lexington MA 02421

Common 07/14/2023 1152 679.33 Wendy Arnold

75 Hayden Avenue Suite 300 Lexington MA 02421

Common 07/17/2023 1774 1206.32 Wendy Arnold

75 Hayden Avenue Suite 300 Lexington MA 02421

Common 07/18/2023 1871 1053.37 Wendy Arnold

75 Hayden Avenue Suite 300 Lexington MA 02421

Common 07/19/2023 1692 1096.25 Wendy Arnold

75 Hayden Avenue Suite 300 Lexington MA 02421

Common 07/20/2023 1716 1109.05 07/21/2023 /s/ Jennifer Ruchti, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Wendy Arnold