Income Taxes - Summary of Reconciliation of the U.S. federal statutory income tax rate to the Company's effective income tax rate (Details) |
12 Months Ended | |
|---|---|---|
Dec. 31, 2021 |
Dec. 31, 2020 |
|
| Income Tax Disclosure [Abstract] | ||
| Federal statutory income tax rate | (21.00%) | (21.00%) |
| State taxes, net of federal benefit | (5.80%) | (6.40%) |
| Federal and state research and development tax credits | (4.40%) | (3.70%) |
| Other | 0.80% | (0.50%) |
| Change in deferred tax asset valuation allowance | 30.40% | 31.60% |
| Effective income tax rate | 0.00% | 0.00% |