Stock-Based Compensation (Tables)
 12 Months Ended
Dec. 31, 2021
Share-based Payment Arrangement [Abstract]  
Schedule of Weighted-Average Assumptions Used to Estimate Fair Value of Stock Options and Restricted Stock Awards using Black-Scholes Option Pricing Model
The following table presents, on a weighted average basis, the assumptions used in the Black-Scholes option-pricing model to determine the grant-date fair value of stock options granted during the years ended December 31, 2021 and 2020 which was as follows:
Year Ended December 31,
20212020
Risk-free interest rate0.7 %0.4 %
Expected volatility78.8 %78.5 %
Expected dividend yield— — 
Expected term (in years)6.06.1
Schedule of Share Option Activity
The following table summarizes the Company’s option activity during the year ended December 31, 2021 which was as follows:
Number of
Shares		Weighted
Average
Exercise
Price		Weighted
Average
Contractual
Term		Aggregate
Intrinsic
Value
(in years)(in thousands)
Outstanding as of December 31, 20205,016,460 $4.93 8.5$76,941 
Granted1,719,563 15.41 
Exercised(508,774)2.79 
Forfeited(306,740)10.22 
Outstanding as of December 31, 20215,920,509 $7.88 7.9$88,720 
Vested and expected to vest as of December 31, 20215,920,509 $7.88 7.9$88,720 
Options exercisable as of December 31, 20212,435,439 $3.62 7.0$46,882 
Summary of Stock-Based Compensation Expense
The Company recorded stock-based compensation expense related to common stock options and restricted common stock in the following expense categories of its consolidated statements of operations and comprehensive loss during the years ended December 31, 2021 and 2020 which was as follows (in thousands):
Year Ended December 31,
20212020
Research and development expenses$4,324 $1,724 
General and administrative expenses4,060 1,237 
$8,384 $2,961