Commitments and Contingencies (Commercial Development Agreement) - Additional Information (Detail) - Master Collaboration Agreement [Member] - Qiagen [Member]
$ in Thousands
12 Months Ended
Dec. 31, 2015
USD ($)
Other Commitments [Line Items]  
Contingent milestone payment $ 1,000
Agreement termination period by the company 180 days
Agreement termination period by both parties 60 days