Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands |
12 Months Ended |
Dec. 31, 2015 |
Dec. 31, 2014 |
Dec. 31, 2013 |
| Income Statement [Abstract] |
|
|
|
| Revenue |
$ 0
|
$ 0
|
$ 0
|
| Operating expenses: |
|
|
|
| Research and development |
32,638
|
14,577
|
12,201
|
| General and administrative |
12,623
|
8,885
|
3,548
|
| Total operating expenses |
45,261
|
23,462
|
15,749
|
| Loss from operations |
(45,261)
|
(23,462)
|
(15,749)
|
| Interest and other income (expense), net |
174
|
166
|
24
|
| Net loss |
(45,087)
|
(23,296)
|
(15,725)
|
| Accretion of redeemable convertible preferred stock to redemption value |
|
|
(94)
|
| Net loss attributable to common stockholders |
$ (45,087)
|
$ (23,296)
|
$ (15,819)
|
| Net loss per share attributable to common stockholders, basic and diluted |
$ (2.01)
|
$ (3.60)
|
$ (38.02)
|
| Weighted average common shares outstanding, basic and diluted |
22,484,343
|
6,469,289
|
416,037
|
| Comprehensive loss: |
|
|
|
| Net loss |
$ (45,087)
|
$ (23,296)
|
$ (15,725)
|
| Other comprehensive loss: |
|
|
|
| Unrealized loss on marketable securities |
(55)
|
|
|
| Total other comprehensive loss |
(55)
|
|
|
| Total comprehensive loss |
$ (45,142)
|
$ (23,296)
|
$ (15,725)
|