In-process research and development and goodwill (Details) (USD $)
12 Months Ended
Dec. 31, 2012
Dec. 31, 2013
Dec. 31, 2011
Segment Reporting Information [Line Items]      
Goodwill $ 5,502,000 $ 13,954,000 $ 5,502,000
Impairment of IPR&D assets 9,600,000    
Biosciences [Member]
     
Segment Reporting Information [Line Items]      
Goodwill 5,502,000 5,502,000 5,502,000
Biodefense [Member]
     
Segment Reporting Information [Line Items]      
Goodwill $ 0 $ 8,452,000 $ 0