Stock-based Compensation (Tables)
12 Months Ended
Dec. 31, 2021
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]  
Summary of Assumptions Used to Determine Grant-Date Fair Value of Options Granted

The assumptions that the Company used to determine the grant-date fair value of options granted were as follows:

 

 

 

Year Ended December 31,

 

 

 

2021

 

 

2020

 

Expected volatility

 

74%

 

 

75%

 

Risk-free interest rate

 

0.82% — 1.34%

 

 

0.31% — 1.67%

 

Expected term (in years)

 

6

 

 

 

6

 

Expected dividend yield

 

 

 

 

 

 

 

Summary of Stock Option Activity and Related Information

The following table summarizes the option activity:

 

(in thousands, except share and per share data)

 

Options

 

 

Weighted
Average
Exercise
Price

 

 

Weighted
Average
Remaining
Life (in years)

 

 

Aggregate
Intrinsic
Value

 

Outstanding January 1, 2021

 

 

6,421,589

 

 

$

6.97

 

 

 

9.5

 

 

$

90,112

 

Granted

 

 

2,240,816

 

 

 

15.84

 

 

 

 

 

 

 

Exercised

 

 

(147,499

)

 

 

3.96

 

 

 

 

 

 

 

Canceled

 

 

(547,156

)

 

 

9.44

 

 

 

 

 

 

 

Outstanding December 31, 2021

 

 

7,967,750

 

 

$

9.35

 

 

 

8.7

 

 

$

36,946

 

Options exercisable— December 31, 2021

 

 

1,872,885

 

 

$

6.13

 

 

 

8.7

 

 

$

13,227

 

Options vested or expected to vest— December 31, 2021

 

 

7,967,750

 

 

$

9.35

 

 

 

8.2

 

 

$

36,946

 

Summary of RSU Activity A summary of the Company’s RSU activity and related information for the 2020 Plan for the year ended December 31, 2021 is as follows:

 

 

 

Number of Shares Underlying RSUs

 

 

Weighted Average
Grant Date Fair Value

 

Issued and unvested as of January 1, 2021

 

 

403,355

 

 

$

23.60

 

Granted

 

 

793,629

 

 

 

14.76

 

Vested

 

 

(93,500

)

 

 

23.69

 

Forfeited

 

 

(46,500

)

 

 

23.35

 

Issued and unvested as of December 31, 2021

 

 

1,056,984

 

 

$

16.99

 

Summary of Restricted Common Stock Award Activity The following table summarizes the Company’s restricted common stock award activity for the year ended December 31, 2021:

 

 

 

Number of Restricted Shares

 

Issued and unvested as of January 1, 2021

 

 

370,329

 

Vested

 

 

(251,808

)

Forfeited

 

 

(80,380

)

Issued and unvested as of December 31, 2021

 

 

38,141

 

Summary of Stock-based Compensation Expense

The Company recorded stock-based compensation expense in the following expense categories of its statements of operations:

 

 

 

Year Ended December 31,

 

(in thousands)

 

2021

 

 

2020

 

Research and development

 

$

7,328

 

 

$

2,699

 

General and administrative

 

 

10,214

 

 

 

3,892

 

Total

 

$

17,542

 

 

$

6,591