Income Taxes - Deferred Tax Assets (Detail) - USD ($)
$ in Thousands
Dec. 31, 2015
Dec. 31, 2014
Deferred tax assets:    
Net operating loss carryforwards $ 37,017 $ 41,846
Capitalized research and development costs 2,431 2,646
Research and development credit carryforwards 3,510 2,360
Stock compensation 5,369 2,479
Depreciation and other costs   372
Depreciation and other costs (74)  
Net deferred tax assets 48,253 49,703
Valuation allowance (48,253) (49,703)
Net deferred tax assets $ 0 $ 0