Consolidated Statements of Convertible Preferred Stock and Stockholders' Equity (Deficit) - USD ($)
$ in Thousands
Total
Cumulative Effect Adjustment of Accounting Method Change
Convertible notes
LifeSci Capital LLC
Private Placement
At-The Market Offering
Series A convertible preferred stock
Series A convertible preferred stock
Series A and B Convertible Preferred Stock
Series B-1 Convertible Preferred Stock
Series C-2 Convertible Preferred Stock
Series C-2 Convertible Preferred Stock
Convertible notes
Series B-2 Convertible Preferred Stock
Series B-2 Convertible Preferred Stock
Series A and B Convertible Preferred Stock
Common stock
Common stock
Series A and B Convertible Preferred Stock
Common stock
Convertible notes
Common stock
LifeSci Capital LLC
Common stock
Private Placement
Common stock
At-The Market Offering
Additional paid-in capital
Additional paid-in capital
Convertible notes
Additional paid-in capital
LifeSci Capital LLC
Additional paid-in capital
Private Placement
Additional paid-in capital
At-The Market Offering
Accumulated deficit
Accumulated deficit
Cumulative Effect Adjustment of Accounting Method Change
Accumulated other comprehensive loss
Balance at Dec. 31, 2018 $ (5,355) $ (45)                       $ 1           $ 66,021         $ (71,377) $ (45)  
Balance, Shares at Dec. 31, 2018                   1,524,122       4,411,567                          
Issuance of common stock, net of issuance costs 934       $ 19,802                             934     $ 19,802        
Issuance of common and preferred stock, net of issuance costs, Shares             1,231             726,139       3,076,923                  
Issuance of common stock through conversion     $ 12,687                                   $ 12,687            
Issuance of common stock through conversion, Shares                     (1,524,122)     1,524,122   2,267,042                      
Additional paid in capital assumed in Business Combination 420                                     420              
Issuance of Series A preferred stock at $3,250 per share 4,000                                     4,000              
Reclassification of stockholders’ equity to warrant liability (187)                                     (187)              
Restricted stock unit release (1,569)                                     (1,569)              
Restricted stock unit release, Shares                           339,025                          
Stock-based compensation 1,304                                     1,304              
Net loss (20,130)                                               (20,130)    
Balance at Dec. 31, 2019 11,861                         $ 1           103,412         (91,552)    
Balance, Shares at Dec. 31, 2019             1,231             12,344,818                          
Issuance of common stock, net of issuance costs       $ 1,011 $ 23,889 $ 19,104                               $ 1,011 $ 23,889 $ 19,104      
Issuance of common and preferred stock, net of issuance costs, Shares                 3,199     524         87,790 2,467,724 951,792                
Issuance of Series B-1 convertible preferred stock 30,968                                     30,968              
Issuance of Series B-2 convertible preferred stock 5,071                                     5,071              
Issuance of common stock from option exercises and RSU releases 473                                     473              
Issuance of common stock from option exercises and RSU releases, Shares                           319,522                          
Issuance of common stock from warrant exercises 842                                     842              
Issuance of common stock from warrant exercises, Shares                           230,619                          
Issuance costs in connection with Form?S-1?registration statement (77)                                     (77)              
Issuance of common stock through conversion 1                         $ 1                          
Issuance of common stock through conversion, Shares               (1,231) (3,199)       (524) 3,198,949 1,139,199                        
Reclassification of warrant liability due to Private SPAC Warrants not held by original holder 206                                     206              
Unrealized loss on available-for-sale securities (1)                                                   $ (1)
Stock-based compensation 4,969                                     4,969              
Net loss (36,477)                                               (36,477)    
Balance at Dec. 31, 2020 61,840                         $ 2           189,868         (128,029)   (1)
Balance, Shares at Dec. 31, 2020                           20,740,413                          
Issuance of common stock, net of issuance costs 134,582         $ 23,836               $ 1           134,581       $ 23,836      
Issuance of common and preferred stock, net of issuance costs, Shares                           4,872,881         530,551                
Issuance of common stock from option exercises and RSU releases 793                                     793              
Issuance of common stock from option exercises and RSU releases, Shares                           466,442                          
Issuance of common stock from warrant exercises 72,429                                     72,429              
Issuance of common stock from warrant exercises, Shares                           3,104,520                          
Issuance of common stock from Employee Stock Purchase Plan 966                                     966              
Issuance of common stock from Employee Stock Purchase Plan, Shares                           58,115                          
Reclassification of warrant liability due to Private SPAC Warrants not held by original holder 434                                     434              
Unrealized loss on available-for-sale securities (123)                                                   (123)
Stock-based compensation 13,276                                     13,276              
Net loss (78,335)                                               (78,335)    
Balance at Dec. 31, 2021 $ 229,698                         $ 3           $ 436,183         $ (206,364)   $ (124)
Balance, Shares at Dec. 31, 2021                           29,772,922