Licensing Agreements - Additional Information (Detail) - USD ($)
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3 Months Ended |
12 Months Ended |
Dec. 31, 2015 |
Sep. 30, 2015 |
Jun. 30, 2015 |
Mar. 31, 2015 |
Dec. 31, 2014 |
Sep. 30, 2014 |
Jun. 30, 2014 |
Mar. 31, 2014 |
Dec. 31, 2015 |
Dec. 31, 2014 |
Dec. 31, 2013 |
| Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |
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| Research and development |
$ 7,157,000
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$ 7,092,000
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$ 6,678,000
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$ 5,021,000
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$ 4,701,000
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$ 2,928,000
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$ 2,648,000
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$ 1,495,000
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$ 25,948,000
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$ 11,772,000
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$ 9,700,000
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| Calando Pharmaceuticals, Inc. [Member] |
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| Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |
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| Bankruptcy proceedings, court where petition was filed |
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District of Delaware
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| Bankruptcy petition date filed |
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Mar. 03, 2015
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| Bankruptcy description |
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In March 2014, Calando entered Chapter 7 bankruptcy in the District of Delaware and, as a result, the intellectual property rights the Company has obtained from Calando are subject to potential risks that may arise in connection with bankruptcy.
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| Calando Product License Agreement [Member] | Upon achievement of specified regulatory and commercial milestones [Member] |
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| Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |
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| Milestone payment |
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$ 32,800,000
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| Calando Platform License Agreement [Member] |
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| Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |
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| Milestone payment |
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17,800,000
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| Calando Platform License Agreement [Member] | CRLX301 [Member] |
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| Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |
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| Milestone payment |
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250,000
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| SUNY License Agreement [Member] |
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| Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |
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| Research and development |
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36,000
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30,000
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25,000
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| MIT License Agreement [Member] |
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| Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |
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| Research and development |
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$ 50,000
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$ 10,000
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$ 10,000
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