Commitments - Additional Information (Detail) - USD ($)
$ in Thousands
12 Months Ended
Jul. 09, 2015
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Operating Leased Assets [Line Items]        
Noncancelable operating lease expire date   Feb. 28, 2013    
Noncancelable operating leases renewal option period   3 years    
Deferred liability related to facility lease     $ 41  
Lease amendment, commencement Date   Jul. 11, 2014    
Lease termination date   Dec. 31, 2015    
Noncancelable operating lease rent expenses   $ 920 $ 766 $ 598
Office Laboratory and Vivarium Space Facility Lease [Member]        
Operating Leased Assets [Line Items]        
Noncancelable operating lease expire date   Feb. 28, 2021    
Noncancelable operating leases renewal option period 3 years      
Extended Lease        
Operating Leased Assets [Line Items]        
Noncancelable operating lease expire date   Feb. 28, 2016