Commitments and Contingencies (Details) (USD $)
 12 Months Ended
Dec. 31, 2014
Lawsuit
Dec. 31, 2013
Dec. 31, 2012
Operating leases, future cash payments [Abstract]      
2015 $ 324,000 [1]    
2016 296,000 [1]    
2017 310,000 [1]    
2018 277,000 [1]    
2019 278,000 [1]    
Thereafter 59,000 [1]    
Total 1,544,000 [1]    
Lease expense 335,991 315,134 324,536
Employment agreements, future cash payments [Abstract]      
2015 2,915,000 [2]    
2016 1,000,000 [2]    
2017 1,000,000 [2]    
2018 1,000,000 [2]    
2019 0 [2]    
Thereafter 0 [2]    
Total 5,915,000 [2]    
Subtotal, future cash payments due [Abstract]      
2015 3,239,000    
2016 1,296,000    
2017 1,310,000    
2018 1,277,000    
2019 278,000    
Thereafter 59,000    
Total 7,459,000    
Research and development, future cash payments due [Abstract]      
2015 26,803,000 [3]    
2016 18,142,000 [3]    
2017 7,367,000 [3]    
2018 1,310,000 [3]    
2019 0 [3]    
Thereafter 0 [3]    
Total 53,622,000 [3]    
Total, future minimum payments due [Abstract]      
2015 30,042,000    
2016 19,438,000    
2017 8,677,000    
2018 2,587,000    
2019 278,000    
Thereafter 59,000    
Total 61,081,000    
Loss Contingencies [Line Items]      
Number of shareholders lawsuits 3    
Legal fees 6,300,000    
Legal fees to be reimbursed by insurance carrier 5,300,000    
Receivables carried to balance sheet $ 1,900,000    
Fishman v. Kriegsman [Member]      
Loss Contingencies [Line Items]      
Number of external investor and public relations firms unaffiliated with company 2    
Silverberg v. Kriegsman [Member]      
Loss Contingencies [Line Items]      
Number of external investor and public relations firms unaffiliated with company 2    
Pankratz v. Kriegsman [Member]      
Loss Contingencies [Line Items]      
Number of external investor and public relations firms unaffiliated with company 2    
Taylor v. Kriegsman [Member]      
Loss Contingencies [Line Items]      
Number of external investor and public relations firms unaffiliated with company 2    
[1] Operating leases are primarily facility lease related obligations, as well as equipment lease obligations with third party vendors. The Company recognized rent expenses of $335,991, $315,134, and $324,536 in 2014, 2013 and 2012, respectively.
[2] Employment agreements include management contracts which have been revised from time to time. The employment agreement for the Company's President and Chief Executive Officer provides for a minimum salary level, which is adjusted annually at the discretion of the Company's Compensation Committee, as well as for minimum bonuses that are payable. New employment agreements for the Company's other executive officers are usually entered into annually or biennially.
[3] Research and development obligations relate primarily to clinical trials. Most of these purchase obligations are cancelable.