INCOME TAXES: - The principal components of the Company's deferred tax assets and liabilities (Details) - USD ($)
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Deferred tax assets:      
Net operating loss carryforward $ 27,190,654 $ 22,301,154 $ 20,843,902
Stock Options 1,203,272 305,982 329,726
Research and development credit carryforward 2,687,591 2,194,211 1,720,558
Accruals and others 232,665 135,330 56,461
Lease liability 3,997,114 289,287 300,991
Gross deferred tax assets 35,311,296 25,225,964 23,251,638
Less valuation allowance (31,242,130) (24,794,474) (22,857,741)
Deferred Tax Assets, Net of Valuation Allowance 4,069,166 431,490 393,897
Deferred tax liability:      
Fixed Assets (4,069,166) (431,490) (393,897)
Net deferred tax assets $ 0 $ 0 $ 0