Document and Entity Information - USD ($)
 12 Months Ended
Dec. 31, 2021
Mar. 09, 2022
Jun. 30, 2021
Document and Entity Information      
Document Type 10-K    
Document Annual Report true    
Document Transition Report false    
Document Period End Date Dec. 31, 2021    
Entity File Number 001-36792    
ICFR Auditor Attestation Flag true    
Entity Registrant Name CYTOSORBENTS CORPORATION    
Entity Incorporation, State or Country Code DE    
Entity Tax Identification Number 98-0373793    
Entity Address, Address Line One 7 Deer Park Drive    
Entity Address, Address Line Two Suite K    
Entity Address, City or Town Monmouth Junction    
Entity Address, State or Province NJ    
Entity Address, Postal Zip Code 08852    
City Area Code 732    
Local Phone Number 329-8885    
Title of 12(b) Security Common Stock, $0.001 par value    
Trading Symbol CTSO    
Security Exchange Name NASDAQ    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Entity Filer Category Non-accelerated Filer    
Entity Small Business true    
Entity Emerging Growth Company false    
Entity Shell Company false    
Entity Common Stock, Shares Outstanding   43,505,948  
Current Fiscal Year End Date --12-31    
Document Fiscal Year Focus 2021    
Document Fiscal Period Focus FY    
Entity Central Index Key 0001175151    
Amendment Flag false    
Entity Public Float     $ 263,355,000
Entity Voluntary Filers No    
Entity Well-known Seasoned Issuer No    
Auditor Name WithumSmith+Brown, PC    
Auditor Firm ID 100    
Auditor Location East Brunswick, New Jersey