STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands |
12 Months Ended |
Dec. 31, 2015 |
Dec. 31, 2014 |
Dec. 31, 2013 |
| Operating activities |
|
|
|
| Net loss |
$ (6,408)
|
$ (31,383)
|
$ (46,011)
|
| Adjustments to reconcile net loss to net cash generated from operations: |
|
|
|
| Stock-based compensation |
6,013
|
5,201
|
5,196
|
| Accretion of interest expense |
2,848
|
3,678
|
4,410
|
| Amortization of debt financing costs |
22
|
29
|
35
|
| Depreciation and amortization of property and equipment |
155
|
141
|
74
|
| Changes in operating assets and liabilities: |
|
|
|
| Trade receivables |
(2,887)
|
(1,906)
|
(871)
|
| Inventory |
815
|
249
|
(883)
|
| Prepaid expenses and other current assets |
799
|
(531)
|
(290)
|
| Other assets |
(7)
|
10
|
(4)
|
| Accounts payable |
(561)
|
(495)
|
(1,423)
|
| Accrued clinical expenses |
835
|
(2,952)
|
2,445
|
| Other accrued liabilities |
1,381
|
575
|
255
|
| Deferred revenue |
125
|
8
|
9
|
| Net cash provided by (used in) operating activities |
3,130
|
(27,376)
|
(37,058)
|
| Investing activities |
|
|
|
| Purchases of property and equipment |
(17)
|
(174)
|
(127)
|
| Cash used in investing activities |
(17)
|
(174)
|
(127)
|
| Financing activities |
|
|
|
| Proceeds from exercise of warrants, net of issuance costs |
17,088
|
|
|
| Proceeds from exercise of stock options, net of issuance costs |
5,193
|
1,777
|
55
|
| Payments related to long-term obligation |
(9,207)
|
(4,856)
|
(1,025)
|
| Net cash provided by (used in) financing activities |
13,074
|
(3,079)
|
(970)
|
| Net increase (decrease) in cash and cash equivalents |
16,187
|
(30,629)
|
(38,155)
|
| Cash and cash equivalents at beginning of period |
24,248
|
54,877
|
93,032
|
| Cash and cash equivalents at end of period |
$ 40,435
|
$ 24,248
|
$ 54,877
|