Summary of IPR&D Intangible Assets and Goodwill (Detail) - USD ($) $ in Thousands |
3 Months Ended | 9 Months Ended | 12 Months Ended | |
|---|---|---|---|---|
Jun. 30, 2016 |
Dec. 31, 2015 |
Sep. 30, 2016 |
Dec. 31, 2015 |
|
| IPR&D intangible assets: | ||||
| Balance at beginning of period | $ 101,500 | |||
| Impairment of intangible asset | $ (104,500) | $ (89,600) | (104,517) | |
| Balance at end of period | 101,500 | $ 101,500 | ||
| Goodwill: | ||||
| Balance at beginning of period | 59,327 | |||
| Balance at end of period | 59,327 | 60,748 | 59,327 | |
| In Process Research and Development | ||||
| IPR&D intangible assets: | ||||
| Balance at beginning of period | 101,500 | 212,900 | ||
| Impairment of intangible asset | $ (104,500) | (104,517) | (89,557) | |
| Change in foreign currency gains (losses) | 3,017 | (21,843) | ||
| Balance at end of period | 101,500 | 0 | 101,500 | |
| Ethical Oncology Science, S.p.A. | ||||
| Goodwill: | ||||
| Balance at beginning of period | 59,327 | 66,055 | ||
| Change in foreign currency gains (losses) | 1,421 | (6,728) | ||
| Balance at end of period | $ 59,327 | $ 60,748 | $ 59,327 | |