Stock-Based Compensation - Weighted-Average Assumptions Used to Estimate Fair Value of Options Granted (Detail) - $ / shares
12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Non-Employee      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Volatility 70.38% 71.76% 75.68%
Risk free interest rate 2.10% 2.44% 1.53%
Dividend yield 0.00% 0.00% 0.00%
Term (years) 8 years 8 months 23 days 9 years 8 months 5 days 7 years 8 months 5 days
Employee Stock Option      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Volatility 60.69% 70.17% 76.60%
Risk free interest rate 1.63% 1.78% 1.79%
Dividend yield 0.00% 0.00% 0.00%
Term (years) 6 years 1 month 17 days 5 years 11 months 23 days 6 years 1 month 21 days
Weighted-average fair value of options granted during the period (usd per share) $ 5.54 $ 5.29 $ 9.85