CONSOLIDATED STATEMENTS OF INCOME (USD $)
In Millions, except Per Share data, unless otherwise specified
 3 Months Ended
Mar. 31, 2015
Mar. 31, 2014
Revenue:    
Net product sales $ 2,055.2 $ 1,707.5
Other revenue 25.6 22.5
Total revenue 2,080.8 1,730.0
Expenses:    
Cost of goods sold (excluding amortization of acquired intangible assets) 104.0 86.1
Research and development 506.0 713.7
Selling, general and administrative 529.2 494.1
Amortization of acquired intangible assets 63.6 65.7
Acquisition related charges, net 19.0 8.6
Total costs and expenses 1,221.8 1,368.2
Operating income 859.0 361.8
Other income and (expense):    
Interest and investment income, net 9.0 6.4
Interest (expense) (49.2) (29.3)
Other income (expense), net 8.3 (6.6)
Income before income taxes 827.1 332.3
Income tax provision 108.2 52.6
Net income $ 718.9 $ 279.7
Net income per common share (Note1):    
Basic (in dollars per share) $ 0.90 $ 0.34
Diluted (in dollars per share) $ 0.86 $ 0.33
Weighted average shares (Note 1):    
Basic (in shares) 798.9 811.5
Diluted (in shares) 834.1 845.1