Note 12 - Subsequent Events (Details) (USD $)
In Millions, except Share data, unless otherwise specified
 0 Months Ended 9 Months Ended 0 Months Ended 12 Months Ended 0 Months Ended
Sep. 23, 2014
Sep. 17, 2014
Feb. 11, 2015
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Feb. 18, 2015
Feb. 18, 2015
Note 12 - Subsequent Events (Details) [Line Items]                
Stock Issued During Period, Shares, New Issues 10,000,000 8,364,379            
Share Price (in Dollars per share)       1.90        
Proceeds From Issuance of Common Stock Gross (in Dollars) $ 20.0 $ 16.6            
Preferred Stock, Shares Issued       10,000 0      
Proceeds from Issuance or Sale of Equity (in Dollars)   16.1            
Payments of Stock Issuance Costs (in Dollars)   0.5            
Series B Convertible Preferred Stock [Member] | Convertible Preferred Stock [Member] | Subsequent Event [Member] | Exchange Agreement With Certain Affiliates of Biotechnology Value Fund [Member]                
Note 12 - Subsequent Events (Details) [Line Items]                
Stock Issued During Period, Shares, New Issues     4,000          
Series B Convertible Preferred Stock [Member] | Convertible Preferred Stock [Member] | Subsequent Event [Member]                
Note 12 - Subsequent Events (Details) [Line Items]                
Preferred Stock, Shares Issued     1,333          
Convertible Preferred Stock, Price Per Share (in Dollars per share)     1,500          
Proceeds From Issuance of Convertible Preferred Stock Gross (in Dollars)     2          
Convertible Preferred Stock to Be Converted     1,000          
Maximum Ownership Percentage Of Common Shares Outstanding Post Conversion     4.99%          
Option Expiration Period     30 days          
Series B Convertible Preferred Stock [Member] | Subsequent Event [Member] | Exchange Agreement With Certain Affiliates of Biotechnology Value Fund [Member]                
Note 12 - Subsequent Events (Details) [Line Items]                
Stock Issued During Period, Shares, New Issues     4,000          
Common Stock [Member] | Subsequent Event [Member] | Exchange Agreement With Certain Affiliates of Biotechnology Value Fund [Member]                
Note 12 - Subsequent Events (Details) [Line Items]                
Common Stock Exchanged for Shares of Convertible Preferred Stock     4,000,000          
Common Stock [Member] | Subsequent Event [Member]                
Note 12 - Subsequent Events (Details) [Line Items]                
Stock Issued During Period, Shares, New Issues     13,500,000          
Share Price (in Dollars per share)     1.50          
Proceeds From Issuance of Common Stock Gross (in Dollars)     20.0          
Common Stock [Member]                
Note 12 - Subsequent Events (Details) [Line Items]                
Stock Issued During Period, Shares, New Issues       11,517,478 13,346,901 13,512,500    
Underwriter Options [Member] | Subsequent Event [Member]                
Note 12 - Subsequent Events (Details) [Line Items]                
Share Price (in Dollars per share)             $ 1.50 $ 1.50
Option Expiration Period     30 days          
Additional Shares Granted, Gross     2,025,000          
Additional Shares Granted, Net             1,199,660  
Proceeds from Issuance or Sale of Equity (in Dollars)             1.7  
Subsequent Event [Member]                
Note 12 - Subsequent Events (Details) [Line Items]                
Proceeds from Issuance or Sale of Equity (in Dollars)               22.4
Proceeds From Issuance or Sale of Equity Gross (in Dollars)               24.0
Payments of Stock Issuance Costs (in Dollars)               $ 1.6