Quarterly Results of Operations - Schedule of Selected Financial Data for Each Quarter (Detail) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 12 Months Ended
Dec. 31, 2016
Sep. 30, 2016
Jun. 30, 2016
Mar. 31, 2016
Dec. 31, 2015
Sep. 30, 2015
Jun. 30, 2015
Mar. 31, 2015
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Quarterly Financial Information Disclosure [Abstract]                      
Revenues     $ 79 $ 7   $ 2,440 $ 874 $ 489 $ 86 $ 3,803 $ 3,177
Net loss - Basic and Diluted $ (21,971) $ (11,542) $ (13,075) $ (10,692) $ (9,530) $ (4,787) $ (5,684) $ (4,689) $ (57,280) $ (24,690) $ (17,745)
Loss per share - Basic and Diluted $ (0.81) $ (0.42) $ (0.48) $ (0.39) $ (0.35) $ (0.19) $ (0.25) $ (0.21) $ (2.10) $ (1.00) $ (0.85)