Stock-Based Compensation - Summary of Assumptions Used in Black-Scholes Option Pricing Model (Detail)
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Risk-free interest rate, minimum 1.19% 1.43% 1.64%
Risk-free interest rate, maximum 1.93% 1.89% 2.72%
Expected volatility, minimum 67.80% 64.00% 64.90%
Expected volatility, maximum 77.80% 67.40% 71.30%
Expected dividend yield 0.00% 0.00% 0.00%
Employee and Board of Directors Options [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Expected life of options (in years) 6 years 3 months 6 years 3 months 6 years 3 months
Nonemployee Options [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Expected life of options (in years) 10 years 10 years 10 years