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West Pharmaceutical Services, Inc. 100.00000000 360.00000000 USD 2023-05-19 XXXX -4572.36000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -31.00000000 NC USD -7750.00000000 -0.00132600853 N/A DE IE N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written ICON PLC ICON PLC 100.00000000 240.00000000 USD 2023-04-21 XXXX 20838.99000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -161.00000000 NC USD -35098.00000000 -0.00600519322 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Johnson & Johnson Johnson & Johnson 100.00000000 160.00000000 USD 2023-05-19 XXXX -1325.16000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -22.00000000 NC USD -27170.00000000 -0.00464872927 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written McKesson Corp. 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Masimo Corp. 100.00000000 165.00000000 USD 2023-04-21 XXXX -19919.41000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -28.00000000 NC USD -1750.00000000 -0.00029942128 N/A DE IE N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Horizon Therapeutics PLC Horizon Therapeutics PLC 100.00000000 110.00000000 USD 2023-04-21 XXXX 1820.30000000 N N N SUSQUEHANNA FINANCIAL GROUP LLLP 549300HN4UKV1E2R3U73 000000000 -38.00000000 NC USD -111865.96000000 -0.01914002807 N/A DE US N 2 SUSQUEHANNA FINANCIAL GROUP LLLP 549300HN4UKV1E2R3U73 Call Written West Pharmaceutical Services, Inc. West Pharmaceutical Services, Inc. 100.00000000 329.00000000 USD 2023-05-19 XXXX -47351.18000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -26.00000000 NC USD -520.00000000 -0.00008897089 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Design Therapeutics, Inc. Design Therapeutics, Inc. 100.00000000 10.00000000 USD 2023-04-21 XXXX 228.02000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -23.00000000 NC USD -118450.00000000 -0.02026654333 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Regeneron Pharmaceuticals, Inc. Regeneron Pharmaceuticals, Inc. 100.00000000 770.00000000 USD 2023-03-31 XXXX -75423.51000000 N N N CONTRA ABIOMED INC N/A 003CVR016 14359.00000000 NS USD 40061.61000000 0.006854456353 Long CORP US N 3 N N N MORGAN STANLEY & CO. INTERNATIONAL 4PQUHN3JPFGFNF3BB653 000000000 -900.00000000 NC -263.16000000 -0.00004502611 N/A DE US N 2 MORGAN STANLEY & CO. INTERNATIONAL 4PQUHN3JPFGFNF3BB653 Call Written Genmab AS Genmab AS 1.00000000 2707.91000000 DKK 2023-04-05 XXXX 6832.32000000 N N N BARCLAYS BANK PLC G5GSEF7VJP5I7OUK5573 000000000 -6700.00000000 NC USD -1495.84000000 -0.00025593504 N/A DE US N 2 BARCLAYS BANK PLC G5GSEF7VJP5I7OUK5573 Call Written Rhythm Pharmaceuticals, Inc. Rhythm Pharmaceuticals, Inc. 1.00000000 28.00000000 USD 2023-05-04 XXXX 9876.07000000 N N N Daiichi Sankyo Co Ltd 353800XGIU2IHQGC9504 000000000 106000.00000000 NS 3866629.37000000 0.661572069893 Long EC CORP JP N 2 N N N Nuvation Bio Inc N/A 67080N119 4050.00000000 NS USD 486.00000000 0.000083153567 N/A DE US N 1 N/A N/A Call Purchased Nuvation Bio Inc Nuvation Bio Inc 1.00000000 11.50000000 USD 2027-07-07 XXXX -7570.78000000 N N N Insulet Corp 549300TZTYD2PYN92D43 45784P101 8555.00000000 NS USD 2728702.80000000 0.466875251485 Long EC CORP US N 1 N N N Align Technology Inc 549300N5YSE0U3LCP840 016255101 3960.00000000 NS USD 1323194.40000000 0.226395750487 Long EC CORP US N 1 N N N Viking Therapeutics Inc 529900IVC72YPFA25M37 92686J106 16970.00000000 NS USD 282550.50000000 0.048343790223 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -65.00000000 NC USD -1625.00000000 -0.00027803404 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written UnitedHealth Group, Inc. UnitedHealth Group, Inc. 100.00000000 500.00000000 USD 2023-04-06 XXXX 41229.47000000 N N N Becton Dickinson & Co ICE2EP6D98PQUILVRZ91 075887109 36070.00000000 NS USD 8928767.80000000 1.527693199889 Long EC CORP US N 1 N N N JEFFERIES LLC 58PU97L1C0WSRCWADL48 000000000 -136.00000000 NC USD -52766.64000000 -0.00902825999 N/A DE US N 2 JEFFERIES LLC 58PU97L1C0WSRCWADL48 Call Written Alcon, Inc. Alcon, Inc. 100.00000000 68.50000000 USD 2023-05-01 XXXX -37429.92000000 N N N Penumbra Inc 549300RGE06P3ECANU72 70975L107 21510.00000000 NS USD 5994621.90000000 1.025667070493 Long EC CORP US N 1 N N N REVOLUTION Medicines Inc 549300JU3X0LBCQ65892 76155X100 18874.00000000 NS USD 408810.84000000 0.069946666135 Long EC CORP US N 1 N N N IQVIA Holdings Inc 549300W3R20NM4KQPH86 46266C105 26058.00000000 NS USD 5182675.62000000 0.886744787103 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -32.00000000 NC USD -4160.00000000 -0.00071176716 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Rhythm Pharmaceuticals, Inc. Rhythm Pharmaceuticals, Inc. 100.00000000 20.00000000 USD 2023-05-19 XXXX -627.39000000 N N N NOMURA SECURITIES INTERNATIONAL INC OXTKY6Q8X53C9ILVV871 000000000 -75.00000000 NC USD -245.48000000 -0.00004200110 N/A DE US N 2 NOMURA SECURITIES INTERNATIONAL INC OXTKY6Q8X53C9ILVV871 Call Written Avantor, Inc. Avantor, Inc. 100.00000000 25.29000000 USD 2023-04-21 XXXX 6412.18000000 N N N Moderna Inc 549300EI6OKH5K5Q2G38 60770K107 28938.00000000 NS USD 4444298.04000000 0.760409951974 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -38.00000000 NC USD -22610.00000000 -0.00386852296 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Intuitive Surgical, Inc. Intuitive Surgical, Inc. 100.00000000 265.00000000 USD 2023-04-28 XXXX 2052.60000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -105.00000000 NC USD -67200.00000000 -0.01149777722 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Becton Dickinson & Co. Becton Dickinson & Co. 100.00000000 245.00000000 USD 2023-04-28 XXXX -32784.33000000 N N N JP MORGAN CHASE BANK 7H6GLXDRUGQFU57RNE97 000000000 -7300.00000000 NC USD -2670.71000000 -0.00045695280 N/A DE US N 2 JP MORGAN CHASE BANK 7H6GLXDRUGQFU57RNE97 Call Written Bausch & Lomb Corp. Bausch & Lomb Corp. 1.00000000 18.35000000 USD 2023-04-24 XXXX 5533.03000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -53.00000000 NC USD -3180.00000000 -0.00054409124 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Baxter International, Inc. Baxter International, Inc. 100.00000000 41.00000000 USD 2023-04-14 XXXX 93.83000000 N N N Stryker Corp 5493002F0SC4JTBU5137 863667101 65135.00000000 NS USD 18594088.45000000 3.181409027481 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -44.00000000 NC USD -16060.00000000 -0.00274783187 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Apellis Pharmaceuticals, Inc. Apellis Pharmaceuticals, Inc. 100.00000000 65.00000000 USD 2023-04-21 XXXX 15491.97000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -58.00000000 NC USD -89900.00000000 -0.01538169899 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Intuitive Surgical, Inc. Intuitive Surgical, Inc. 100.00000000 240.00000000 USD 2023-03-31 XXXX -61240.36000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -13.00000000 NC USD -6825.00000000 -0.00116774299 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Prometheus Biosciences, Inc. Prometheus Biosciences, Inc. 100.00000000 125.00000000 USD 2023-05-19 XXXX 5365.92000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -109.00000000 NC USD -24252.50000000 -0.00414955122 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Dexcom, Inc. Dexcom, Inc. 100.00000000 120.00000000 USD 2023-04-21 XXXX 26188.36000000 N N N JANE STREET EXECUTION SERVICES, LLC 549300HXJLXCPDWAH070 000000000 -28.00000000 NC USD -8030.62000000 -0.00137402201 N/A DE US N 2 JANE STREET EXECUTION SERVICES, LLC 549300HXJLXCPDWAH070 Call Written Zimmer Biomet Holdings, Inc. Zimmer Biomet Holdings, Inc. 100.00000000 128.33000000 USD 2023-04-21 XXXX 1902.74000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -50.00000000 NC USD -13125.00000000 -0.00224565961 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Blueprint Medicines Corp. Blueprint Medicines Corp. 100.00000000 50.00000000 USD 2023-05-19 XXXX -486.56000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -75.00000000 NC USD -7125.00000000 -0.00121907236 N/A DE IE N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Medtronic PLC Medtronic PLC 100.00000000 85.00000000 USD 2023-05-19 XXXX 285.06000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -55.00000000 NC USD -5912.50000000 -0.00101161618 N/A DE CA N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Bausch & Lomb Corp. Bausch & Lomb Corp. 100.00000000 17.50000000 USD 2023-05-19 XXXX -2845.13000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -201.00000000 NC USD -87435.00000000 -0.01495994272 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written AbbVie, Inc. AbbVie, Inc. 100.00000000 155.00000000 USD 2023-03-31 XXXX -54718.80000000 N N N AstraZeneca PLC PY6ZZQWO2IZFZC3IOL08 046353108 24607.00000000 NS USD 1707971.87000000 0.292230358079 Long EC CORP GB N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -767.00000000 NC USD -118885.00000000 -0.02034097090 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Boston Scientific Corp. Boston Scientific Corp. 100.00000000 49.00000000 USD 2023-04-21 XXXX -48880.75000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -83.00000000 NC USD -4772.50000000 -0.00081656461 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Pfizer, Inc. Pfizer, Inc. 100.00000000 41.00000000 USD 2023-04-14 XXXX 1516.43000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -61.00000000 NC USD -30042.50000000 -0.00514020791 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Elevance Health, Inc. Elevance Health, Inc. 100.00000000 480.00000000 USD 2023-04-28 XXXX 23026.99000000 N N N Cigna Group/The 549300VIWYMSIGT1U456 125523100 13289.00000000 NS USD 3395738.17000000 0.581003586061 Long EC CORP US N 1 N N N Structure Therapeutics Inc N/A 86366E106 13208.00000000 NS USD 314218.32000000 0.053762086941 Long EC CORP KY N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -80.00000000 NC USD -23200.00000000 -0.00396947070 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Envista Holdings Corp. Envista Holdings Corp. 100.00000000 39.00000000 USD 2023-04-21 XXXX -13561.57000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -26.00000000 NC USD -12480.00000000 -0.00213530148 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Arvinas, Inc. Arvinas, Inc. 100.00000000 40.00000000 USD 2023-04-21 XXXX -7553.71000000 N N N Enanta Pharmaceuticals Inc 529900SSN4DODDQSN594 29251M106 3150.00000000 NS USD 127386.00000000 0.021795473946 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -53.00000000 NC USD -17278.00000000 -0.00295622908 N/A DE IE N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Medtronic PLC Medtronic PLC 100.00000000 78.00000000 USD 2023-04-28 XXXX -3881.25000000 N N N Illumina Inc SQ95QG8SR5Q56LSNF682 452327109 12680.00000000 NS USD 2948734.00000000 0.504522122311 Long EC CORP US N 1 N N CITIBANK NA E57ODZWZ7FF32TWEFA76 000000000 -2700.00000000 NC USD -12425.32000000 -0.00212594585 N/A DE US N 2 CITIBANK NA E57ODZWZ7FF32TWEFA76 Call Written Zimmer Biomet Holdings, Inc. Zimmer Biomet Holdings, Inc. 1.00000000 126.95900000 USD 2023-04-27 XXXX -4369.87000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -32.00000000 NC USD -2400.00000000 -0.00041063490 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written McKesson Corp. McKesson Corp. 100.00000000 370.00000000 USD 2023-03-31 XXXX 12947.13000000 N N N Mirati Therapeutics Inc 529900GYRW59IDQV6N54 60468T105 15380.00000000 NS USD 571828.40000000 0.097838624293 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -101.00000000 NC USD -161600.00000000 -0.02764941665 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Thermo Fisher Scientific, Inc. Thermo Fisher Scientific, Inc. 100.00000000 560.00000000 USD 2023-03-31 XXXX -25478.26000000 N N N Orchestra BioMed Holdings Inc N/A 68572M106 13696.00000000 NS USD 268030.72000000 0.045859486715 Long EC CORP US N 1 N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -81.00000000 NC USD -122715.00000000 -0.02099627577 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Penumbra, Inc. Penumbra, Inc. 100.00000000 270.00000000 USD 2023-04-21 XXXX -34606.26000000 N N N Cerevel Therapeutics Holdings Inc 254900RJNIRS9COSQR41 15678U128 16785.00000000 NS USD 409386.15000000 0.070045100454 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -31.00000000 NC USD -8447.50000000 -0.00144534930 N/A DE IE N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written STERIS PLC STERIS PLC 100.00000000 200.00000000 USD 2023-04-21 XXXX 4180.69000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -51.00000000 NC USD -3570.00000000 -0.00061081941 N/A DE JE N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Novocure Ltd. Novocure Ltd. 100.00000000 100.00000000 USD 2023-04-21 XXXX 14660.29000000 N N N Affinivax Inc., N/A 000000000 6331.00000000 NS USD 83126.03000000 0.014222687117 Long EC CORP US Y 3 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -6.00000000 NC USD -2520.00000000 -0.00043116664 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Krystal Biotech, Inc. Krystal Biotech, Inc. 100.00000000 85.00000000 USD 2023-04-21 XXXX -1528.92000000 N N N Guardant Health Inc N/A 40131M109 11675.00000000 NS USD 273662.00000000 0.046822986758 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -126.00000000 NC USD -882.00000000 -0.00015090832 N/A DE IE N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Medtronic PLC Medtronic PLC 100.00000000 87.50000000 USD 2023-04-21 XXXX 33304.35000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -29.00000000 NC USD -1377.50000000 -0.00023568732 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Ionis Pharmaceuticals, Inc. Ionis Pharmaceuticals, Inc. 100.00000000 40.00000000 USD 2023-05-19 XXXX 733.85000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -33.00000000 NC USD -14850.00000000 -0.00254080344 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written ResMed, Inc. ResMed, Inc. 100.00000000 220.00000000 USD 2023-04-21 XXXX 7669.34000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -129.00000000 NC USD -39990.00000000 -0.00684220403 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Amgen, Inc. Amgen, Inc. 100.00000000 245.00000000 USD 2023-04-21 XXXX -10607.79000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -65.00000000 NC USD -975.00000000 -0.00016682042 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Rocket Pharmaceuticals, Inc. Rocket Pharmaceuticals, Inc. 100.00000000 22.50000000 USD 2023-04-21 XXXX 6167.10000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -12.00000000 NC USD -3960.00000000 -0.00067754758 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Omnicell, Inc. Omnicell, Inc. 100.00000000 60.00000000 USD 2023-04-21 XXXX -1286.82000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -63.00000000 NC USD -8820.00000000 -0.00150908326 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Agilent Technologies, Inc. Agilent Technologies, Inc. 100.00000000 150.00000000 USD 2023-05-19 XXXX 9624.42000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -194.00000000 NC USD -28615.00000000 -0.00489596570 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Baxter International, Inc. Baxter International, Inc. 100.00000000 41.00000000 USD 2023-04-28 XXXX -1887.66000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -4.00000000 NC USD -300.00000000 -0.00005132936 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written AmerisourceBergen Corp. AmerisourceBergen Corp. 100.00000000 165.00000000 USD 2023-03-31 XXXX 494.54000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -23.00000000 NC USD -15870.00000000 -0.00271532328 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written AmerisourceBergen Corp. AmerisourceBergen Corp. 100.00000000 155.00000000 USD 2023-04-28 XXXX -9468.88000000 N N N Incyte Corp 549300Z4WN6JVZ3T4680 45337C102 33358.00000000 NS USD 2410782.66000000 0.412479791006 Long EC CORP US N 1 N N N Krystal Biotech Inc 549300YONUY68210OE41 501147102 3135.00000000 NS USD 250988.10000000 0.042943530642 Long EC CORP US N 1 N N N JP MORGAN CHASE BANK 7H6GLXDRUGQFU57RNE97 000000000 -22500.00000000 NC -77039.02000000 -0.01318121263 N/A DE US N 2 JP MORGAN CHASE BANK 7H6GLXDRUGQFU57RNE97 Call Written Daiichi Sankyo Co. Ltd. Daiichi Sankyo Co. Ltd. 1.00000000 4374.24000000 JPY 2023-04-04 XXXX -58154.22000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -35.00000000 NC USD -437.50000000 -0.00007485532 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Exact Sciences Corp. Exact Sciences Corp. 100.00000000 68.00000000 USD 2023-03-31 XXXX 3903.19000000 N N N Nautilus Biotechnology Inc N/A 63909J108 16560.00000000 NS USD 45871.20000000 0.007848464858 Long EC CORP US N 1 N N N AstraZeneca PLC PY6ZZQWO2IZFZC3IOL08 000000000 41126.00000000 NS 5698182.90000000 0.974946987428 Long EC CORP GB N 2 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -52.00000000 NC USD -3640.00000000 -0.00062279626 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written BioMarin Pharmaceutical, Inc. BioMarin Pharmaceutical, Inc. 100.00000000 115.00000000 USD 2023-04-21 XXXX 13143.70000000 N N N Intuitive Surgical Inc 54930052SRG011710797 46120E602 56844.00000000 NS USD 14521936.68000000 2.484672511615 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -111.00000000 NC USD -1665.00000000 -0.00028487796 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Centene Corp. Centene Corp. 100.00000000 70.00000000 USD 2023-04-06 XXXX 20803.14000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -12.00000000 NC USD -4620.00000000 -0.00079047218 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Omnicell, Inc. Omnicell, Inc. 100.00000000 60.00000000 USD 2023-05-19 XXXX -2246.77000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -72.00000000 NC USD -68220.00000000 -0.01167229705 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Moderna, Inc. Moderna, Inc. 100.00000000 145.00000000 USD 2023-04-06 XXXX -31983.79000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -23.00000000 NC USD -1092.50000000 -0.00018692442 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Ultragenyx Pharmaceutical, Inc. Ultragenyx Pharmaceutical, Inc. 100.00000000 50.00000000 USD 2023-04-21 XXXX 11306.79000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -27.00000000 NC USD -59670.00000000 -0.01020941022 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written IDEXX Laboratories, Inc. 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Avantor, Inc. 100.00000000 22.50000000 USD 2023-05-19 XXXX -164.00000000 N N N Immunocore Holdings PLC 213800IUE3DFS84BVN18 45258D105 9668.00000000 NS USD 477985.92000000 0.081782375349 Long EC CORP GB N 1 N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -48.00000000 NC USD -53040.00000000 -0.00907503130 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Illumina, Inc. Illumina, Inc. 100.00000000 230.00000000 USD 2023-04-21 XXXX -29337.18000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -5.00000000 NC USD -1240.00000000 -0.00021216136 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Moderna, Inc. Moderna, Inc. 100.00000000 170.00000000 USD 2023-04-28 XXXX 1036.35000000 N N N Goldfinch Bio, Inc. SERIES B N/A 000000000 190000.00000000 NS USD 62700.00000000 0.010727836783 Long EC CORP US Y 3 N N N JP MORGAN CHASE BANK 7H6GLXDRUGQFU57RNE97 000000000 -4700.00000000 NC -46230.13000000 -0.00790987701 N/A DE US N 2 JP MORGAN CHASE BANK 7H6GLXDRUGQFU57RNE97 Call Written Sanofi Sanofi 1.00000000 91.73500000 EUR 2023-04-27 XXXX -35978.67000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -22.00000000 NC USD -154.00000000 -0.00002634907 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Moderna, Inc. Moderna, Inc. 100.00000000 160.00000000 USD 2023-03-31 XXXX 4163.05000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -70.00000000 NC USD -65800.00000000 -0.01125824019 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Vertex Pharmaceuticals, Inc. Vertex Pharmaceuticals, Inc. 100.00000000 315.00000000 USD 2023-04-28 XXXX -10733.67000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -65.00000000 NC USD -617.50000000 -0.00010565293 N/A DE IE N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Medtronic PLC Medtronic PLC 100.00000000 83.00000000 USD 2023-04-06 XXXX 13537.49000000 N N N Quanta Dialysis Technologies Ltd SERIES D N/A 000000000 4243029.00000000 NS 366393.83000000 0.062689205846 Long EC CORP GB Y 3 N N N Abbott Laboratories HQD377W2YR662HK5JX27 002824100 129731.00000000 NS USD 13136561.06000000 2.247637686500 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -14.00000000 NC USD -12810.00000000 -0.00219176378 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Insulet Corp. Insulet Corp. 100.00000000 320.00000000 USD 2023-04-21 XXXX 3118.42000000 N N N MORGAN STANLEY & CO. INTERNATIONAL 4PQUHN3JPFGFNF3BB653 000000000 -1300.00000000 NC -9.49000000 -0.00000162371 N/A DE US N 2 MORGAN STANLEY & CO. INTERNATIONAL 4PQUHN3JPFGFNF3BB653 Call Written Roche Holding AG Roche Holding AG 1.00000000 288.67580000 CHF 2023-04-11 XXXX 2255.89000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -115.00000000 NC USD -95737.50000000 -0.01638048283 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Eli Lilly & Co. Eli Lilly & Co. 100.00000000 335.00000000 USD 2023-03-31 XXXX -59672.46000000 N N N Exo Imaging, Inc. 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UnitedHealth Group, Inc. 100.00000000 485.00000000 USD 2023-04-28 XXXX -3602.24000000 N N N Morphic Holding Inc 549300RWWOUFLHTY1224 61775R105 7120.00000000 NS USD 267996.80000000 0.045853683075 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -81.00000000 NC USD -38070.00000000 -0.00651369611 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written AmerisourceBergen Corp. AmerisourceBergen Corp. 100.00000000 157.50000000 USD 2023-04-21 XXXX -13343.25000000 N N N CITIBANK NA E57ODZWZ7FF32TWEFA76 000000000 -10400.00000000 NC -32367.21000000 -0.00553796086 N/A DE US N 2 CITIBANK NA E57ODZWZ7FF32TWEFA76 Call Written Daiichi Sankyo Co. Ltd. Daiichi Sankyo Co. 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Neurocrine Biosciences, Inc. 1.00000000 100.46600000 USD 2023-05-15 XXXX -7100.24000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -53.00000000 NC USD -4372.50000000 -0.00074812545 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Edwards Lifesciences Corp. Edwards Lifesciences Corp. 100.00000000 82.00000000 USD 2023-03-31 XXXX 8306.50000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -22.00000000 NC USD -12100.00000000 -0.00207028429 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written 10X Genomics, Inc. 10X Genomics, Inc. 100.00000000 55.00000000 USD 2023-05-19 XXXX -5464.82000000 N N N Dexcom Inc 549300YSK3QDSFR5EU59 252131107 54892.00000000 NS USD 6377352.56000000 1.091151473242 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -16.00000000 NC USD -27120.00000000 -0.00464017437 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Masimo Corp. Masimo Corp. 100.00000000 175.00000000 USD 2023-05-19 XXXX -11127.32000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -74.00000000 NC USD -11248.00000000 -0.00192450890 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Bristol-Myers Squibb Co. Bristol-Myers Squibb Co. 100.00000000 69.00000000 USD 2023-04-28 XXXX -3679.52000000 N N N IVERIC bio Inc 549300GZXI59U71XPM70 46583P102 12230.00000000 NS USD 297555.90000000 0.050911182281 Long EC CORP US N 1 N N N Pfizer Inc 765LHXWGK1KXCLTFYQ30 717081103 206621.00000000 NS USD 8430136.80000000 1.442378495216 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -39.00000000 NC USD -38025.00000000 -0.00650599670 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written McKesson Corp. McKesson Corp. 100.00000000 350.00000000 USD 2023-04-14 XXXX -12174.82000000 N N N Sarepta Therapeutics Inc 549300IKDPIED8J8IG21 803607100 18688.00000000 NS USD 2575767.04000000 0.440708267887 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -38.00000000 NC USD -5396.00000000 -0.00092324413 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Gilead Sciences, Inc. Gilead Sciences, Inc. 100.00000000 82.00000000 USD 2023-04-06 XXXX 813.82000000 N N N JANE STREET EXECUTION SERVICES, LLC 549300HXJLXCPDWAH070 000000000 -138.00000000 NC USD -16206.17000000 -0.00277284125 N/A DE US N 2 JANE STREET EXECUTION SERVICES, LLC 549300HXJLXCPDWAH070 Call Written Zoetis, Inc. Zoetis, Inc. 100.00000000 172.00000000 USD 2023-04-21 XXXX 92641.72000000 N N N Edwards Lifesciences Corp YA13X31F3V31L8TMPR58 28176E108 37566.00000000 NS USD 3107835.18000000 0.531743996171 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -31.00000000 NC USD -14260.00000000 -0.00243985570 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Repligen Corp. 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Rhythm Pharmaceuticals, Inc. 100.00000000 30.00000000 USD 2023-04-21 XXXX 11642.18000000 N N N Legend Biotech Corp 254900EIUFZTW136H859 52490G102 14146.00000000 NS USD 682120.12000000 0.116709303251 Long EC CORP KY N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -6.00000000 NC USD -780.00000000 -0.00013345634 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Karuna Therapeutics, Inc. Karuna Therapeutics, Inc. 100.00000000 220.00000000 USD 2023-05-19 XXXX 2369.00000000 N N N Money Market Series a series of SL Liquidity Series, LLC 549300I0RQO84VDWQP47 590204509 5038011.64000000 NS USD 5038515.44000000 0.862079286598 Long STIV US N N/A N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -62.00000000 NC USD -19065.00000000 -0.00326198099 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Sarepta Therapeutics, Inc. Sarepta Therapeutics, Inc. 100.00000000 135.00000000 USD 2023-03-31 XXXX 3011.17000000 N N N AmerisourceBergen Corp AI8GXW8LG5WK7E9UD086 03073E105 55773.00000000 NS USD 8929815.03000000 1.527872378717 Long EC CORP US N 1 N N N Rapid Micro Biosystems Inc N/A 75340L104 20561.00000000 NS USD 26934.91000000 0.004608505873 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -27.00000000 NC USD -2970.00000000 -0.00050816068 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Exact Sciences Corp. Exact Sciences Corp. 100.00000000 72.50000000 USD 2023-04-21 XXXX 1573.80000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -23.00000000 NC USD -7302.50000000 -0.00124944223 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written AmerisourceBergen Corp. AmerisourceBergen Corp. 100.00000000 160.00000000 USD 2023-04-21 XXXX -1103.07000000 N N N Sanofi 549300E9PC51EN656011 000000000 24587.00000000 NS 2667166.18000000 0.456346466548 Long EC CORP FR N 2 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -102.00000000 NC USD -510.00000000 -0.00008725991 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Incyte Corp. Incyte Corp. 100.00000000 82.50000000 USD 2023-04-21 XXXX 17622.21000000 N N N JANE STREET EXECUTION SERVICES, LLC 549300HXJLXCPDWAH070 000000000 -35.00000000 NC USD -187.50000000 -0.00003208085 N/A DE US N 2 JANE STREET EXECUTION SERVICES, LLC 549300HXJLXCPDWAH070 Call Written REVOLUTION Medicines, Inc. REVOLUTION Medicines, Inc. 100.00000000 30.10000000 USD 2023-04-21 XXXX 13139.55000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -36.00000000 NC USD -3060.00000000 -0.00052355949 N/A DE GB N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Immunocore Holdings PLC Immunocore Holdings PLC 100.00000000 70.00000000 USD 2023-04-21 XXXX 9924.56000000 N N N MORGAN STANLEY & CO. INTERNATIONAL 4PQUHN3JPFGFNF3BB653 000000000 -5000.00000000 NC -51054.24000000 -0.00873527199 N/A DE US N 2 MORGAN STANLEY & CO. INTERNATIONAL 4PQUHN3JPFGFNF3BB653 Call Written Novo Nordisk A/S Novo Nordisk A/S 1.00000000 1016.12000000 DKK 2023-04-05 XXXX -37676.33000000 N N N Prime Medicine Inc N/A 74168J101 22929.00000000 NS USD 282026.70000000 0.048254169156 Long EC CORP US N 1 N N Ultragenyx Pharmaceutical Inc 529900EV44GVDN1DCX77 90400D108 6140.00000000 NS USD 246214.00000000 0.042126692276 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -20.00000000 NC USD -86500.00000000 -0.01479996621 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Regeneron Pharmaceuticals, Inc. Regeneron Pharmaceuticals, Inc. 100.00000000 790.00000000 USD 2023-04-28 XXXX -51119.87000000 N N N ARCUTIS BIOTHERAPEUTICS, INC N/A 03969K108 42854.00000000 NS USD 471394.00000000 0.080654511843 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -210.00000000 NC USD -52710.00000000 -0.00901856900 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Merck & Co., Inc. Merck & Co., Inc. 100.00000000 108.00000000 USD 2023-05-05 XXXX -15793.90000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -21.00000000 NC USD -4305.00000000 -0.00073657635 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Hologic, Inc. Hologic, Inc. 100.00000000 80.00000000 USD 2023-04-21 XXXX -571.85000000 N N N Design Therapeutics Inc N/A 25056L103 13967.00000000 NS USD 80589.59000000 0.013788707622 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -44.00000000 NC USD -4444.00000000 -0.00076035895 N/A DE IE N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Medtronic PLC Medtronic PLC 100.00000000 82.00000000 USD 2023-04-21 XXXX 2101.86000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -31.00000000 NC USD -5812.50000000 -0.00099450640 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Cerevel Therapeutics Holdings, Inc. Cerevel Therapeutics Holdings, Inc. 100.00000000 25.00000000 USD 2023-05-19 XXXX -237.86000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -177.00000000 NC USD -40267.50000000 -0.00688968369 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Baxter International, Inc. Baxter International, Inc. 100.00000000 40.00000000 USD 2023-05-05 XXXX -12273.24000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -18.00000000 NC USD -1260.00000000 -0.00021558332 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written REVOLUTION Medicines, Inc. REVOLUTION Medicines, Inc. 100.00000000 25.00000000 USD 2023-05-19 XXXX 852.55000000 N N N Arvinas Inc N/A 04335A105 15330.00000000 NS USD 418815.60000000 0.071658459314 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -110.00000000 NC USD -605.00000000 -0.00010351421 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Johnson & Johnson Johnson & Johnson 100.00000000 170.00000000 USD 2023-04-21 XXXX 22392.77000000 N N N BlackRock Liquidity Funds 5493007YVNX55LTRQ706 09248U718 20478473.53000000 NS USD 20478473.53000000 3.503823310972 Long STIV RF US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -275.00000000 NC USD -12100.00000000 -0.00207028429 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Pfizer, Inc. Pfizer, Inc. 100.00000000 42.00000000 USD 2023-04-28 XXXX 5022.87000000 N N N Neurocrine Biosciences Inc 549300FECER0XBN49756 64125C109 23254.00000000 NS USD 2353769.88000000 0.402725025482 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -246.00000000 NC USD -2091.00000000 -0.00035776565 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Abbott Laboratories Abbott Laboratories 100.00000000 107.00000000 USD 2023-04-14 XXXX 26962.91000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -26.00000000 NC USD -6565.00000000 -0.00112325755 N/A DE KY N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Legend Biotech Corp. Legend Biotech Corp. 100.00000000 55.00000000 USD 2023-05-19 XXXX 136.88000000 N N N HCA Healthcare Inc 529900PH4ZGUH2MNEU89 40412C101 14645.00000000 NS USD 3861593.60000000 0.660710460345 Long EC CORP US N 1 N N N Masimo Corp 549300Q4A8JK0PIYCU29 574795100 8860.00000000 NS USD 1635024.40000000 0.279749200951 Long EC CORP US N 1 N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -19.00000000 NC USD -2042.50000000 -0.00034946741 N/A DE IE N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Alkermes PLC Alkermes PLC 100.00000000 29.00000000 USD 2023-05-19 XXXX 28.88000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -139.00000000 NC USD -148730.00000000 -0.02544738699 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Eli Lilly & Co. Eli Lilly & Co. 100.00000000 345.00000000 USD 2023-04-28 XXXX -70411.03000000 N N N Avantor Inc N/A 05352A100 78897.00000000 NS USD 1667882.58000000 0.285371165736 Long EC CORP US N 1 N N N McKesson Corp 549300WZWOM80UCFSF54 58155Q103 24550.00000000 NS USD 8741027.50000000 1.495571233445 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -6.00000000 NC USD -1920.00000000 -0.00032850792 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Krystal Biotech, Inc. Krystal Biotech, Inc. 100.00000000 95.00000000 USD 2023-05-19 XXXX 397.19000000 N N N Humana Inc 529900YLDW34GJAO4J06 444859102 9185.00000000 NS USD 4458950.10000000 0.762916888309 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -99.00000000 NC USD -39600.00000000 -0.00677547586 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Dexcom, Inc. Dexcom, Inc. 100.00000000 125.00000000 USD 2023-05-19 XXXX 3146.43000000 N N N Bausch + Lomb Corp 549300NY6OZM39SO6475 071705107 75830.00000000 NS USD 1320200.30000000 0.225883466339 Long EC CORP CA N 1 N N N GOLDMAN SACHS INTERNATIONAL W22LROWP2IHZNBB6K528 000000000 -8900.00000000 NC -28718.30000000 -0.00491364011 N/A DE US N 2 GOLDMAN SACHS INTERNATIONAL W22LROWP2IHZNBB6K528 Call Written AstraZeneca PLC AstraZeneca PLC 1.00000000 114.08330000 GBP 2023-05-10 XXXX -9931.77000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -111.00000000 NC USD -5550.00000000 -0.00094959320 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Cigna Group Cigna Group 100.00000000 305.00000000 USD 2023-03-31 XXXX 36520.99000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -21.00000000 NC USD -92715.00000000 -0.01586333951 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Regeneron Pharmaceuticals, Inc. Regeneron Pharmaceuticals, Inc. 100.00000000 785.00000000 USD 2023-04-21 XXXX -33325.79000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -62.00000000 NC USD -8835.00000000 -0.00151164972 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Sage Therapeutics, Inc. Sage Therapeutics, Inc. 100.00000000 47.50000000 USD 2023-05-19 XXXX 4046.69000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -89.00000000 NC USD -176220.00000000 -0.03015086759 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Thermo Fisher Scientific, Inc. Thermo Fisher Scientific, Inc. 100.00000000 560.00000000 USD 2023-04-14 XXXX -49683.41000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -20.00000000 NC USD -1050.00000000 -0.00017965276 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Sage Therapeutics, Inc. 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Gilead Sciences, Inc. 100.00000000 82.00000000 USD 2023-04-21 XXXX -19466.13000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -75.00000000 NC USD -7800.00000000 -0.00133456342 N/A DE IE N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Medtronic PLC Medtronic PLC 100.00000000 83.00000000 USD 2023-05-05 XXXX 1257.74000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -4.00000000 NC USD -3220.00000000 -0.00055093515 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written iRhythm Technologies, Inc. iRhythm Technologies, Inc. 100.00000000 120.00000000 USD 2023-04-21 XXXX -854.02000000 N N N Regeneron Pharmaceuticals Inc 549300RCBFWIRX3HYQ56 75886F107 17857.00000000 NS USD 14672561.19000000 2.510444045249 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -72.00000000 NC USD -90000.00000000 -0.01539880877 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Intuitive Surgical, Inc. Intuitive Surgical, Inc. 100.00000000 245.00000000 USD 2023-04-14 XXXX -54286.17000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -4.00000000 NC USD -3640.00000000 -0.00062279626 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written iRhythm Technologies, Inc. iRhythm Technologies, Inc. 100.00000000 125.00000000 USD 2023-05-19 XXXX -728.95000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -6.00000000 NC USD -4170.00000000 -0.00071347814 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Waters Corp. Waters Corp. 100.00000000 330.00000000 USD 2023-05-19 XXXX 1236.13000000 N N N CureVac NV 724500BUT8GAG9LMYN56 000000000 20488.00000000 NS USD 142801.36000000 0.024433009290 Long EC CORP NL N 1 N N JANE STREET EXECUTION SERVICES, LLC 549300HN4UKV1E2R3U73 000000000 -47.00000000 NC USD -8137.67000000 -0.00139233804 N/A DE US N 2 JANE STREET EXECUTION SERVICES, LLC 549300HN4UKV1E2R3U73 Call Written Edwards Lifesciences Corp. Edwards Lifesciences Corp. 100.00000000 83.52000000 USD 2023-04-21 XXXX 1580.48000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -74.00000000 NC USD -14800.00000000 -0.00253224855 N/A DE NL N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written QIAGEN NV QIAGEN NV 100.00000000 50.00000000 USD 2023-04-21 XXXX -2755.23000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -75.00000000 NC USD -25875.00000000 -0.00442715752 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written UnitedHealth Group, Inc. UnitedHealth Group, Inc. 100.00000000 495.00000000 USD 2023-04-21 XXXX 26824.24000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -23.00000000 NC USD -632.50000000 -0.00010821940 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Moderna, Inc. Moderna, Inc. 100.00000000 190.00000000 USD 2023-04-21 XXXX 14271.63000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -30.00000000 NC USD -14100.00000000 -0.00241248004 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written IQVIA Holdings, Inc. IQVIA Holdings, Inc. 100.00000000 210.00000000 USD 2023-05-19 XXXX 2332.99000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -134.00000000 NC USD -32495.00000000 -0.00555982545 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Danaher Corp. Danaher Corp. 100.00000000 260.00000000 USD 2023-04-21 XXXX 11799.08000000 N N N Glaukos Corp 5299004JA1LHE21M6T14 377322102 4880.00000000 NS USD 244488.00000000 0.041831377343 Long EC CORP US N 1 N N N Decibel Therapeutics Inc N/A 24343R106 46884.00000000 NS USD 141589.68000000 0.024225693416 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -31.00000000 NC USD -52855.00000000 -0.00904337820 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Cooper Cos., Inc. Cooper Cos., Inc. 100.00000000 370.00000000 USD 2023-05-19 XXXX -33518.02000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -22.00000000 NC USD -880.00000000 -0.00015056613 N/A DE IE N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Alkermes PLC Alkermes PLC 100.00000000 29.00000000 USD 2023-04-21 XXXX 2942.87000000 N N N Rocket Pharmaceuticals Inc 549300R7VV82YUIN4Y93 77313F106 17213.00000000 NS USD 294858.69000000 0.050449695381 Long EC CORP US N 1 N N N Mettler-Toledo International Inc 5493000BD5GJNUDIUG10 592688105 1055.00000000 NS USD 1614371.55000000 0.276215542197 Long EC CORP US N 1 N N N Afferent Pharmaceuticals, Inc. N/A 000000000 190160.00000000 NS USD 150226.40000000 0.025703417858 Long EP CORP US Y 3 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -34.00000000 NC USD -7225.00000000 -0.00123618214 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Elevance Health, Inc. Elevance Health, Inc. 100.00000000 480.00000000 USD 2023-04-14 XXXX 16011.84000000 N N N Encompass Health Corp 549300FVRPM9DRQZRG64 29261A100 15684.00000000 NS USD 848504.40000000 0.145177300047 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -9.00000000 NC USD -1665.00000000 -0.00028487796 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Sarepta Therapeutics, Inc. Sarepta Therapeutics, Inc. 100.00000000 150.00000000 USD 2023-04-21 XXXX 5303.70000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -74.00000000 NC USD -1739.00000000 -0.00029753920 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Bristol-Myers Squibb Co. Bristol-Myers Squibb Co. 100.00000000 70.00000000 USD 2023-04-06 XXXX 9258.46000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -33.00000000 NC USD -5445.00000000 -0.00093162793 N/A DE IE N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Prothena Corp. PLC Prothena Corp. PLC 100.00000000 55.00000000 USD 2023-05-19 XXXX 4121.16000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -40.00000000 NC USD -67600.00000000 -0.01156621637 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Vertex Pharmaceuticals, Inc. Vertex Pharmaceuticals, Inc. 100.00000000 300.00000000 USD 2023-04-14 XXXX -42689.36000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -42.00000000 NC USD -13230.00000000 -0.00226362489 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Edwards Lifesciences Corp. Edwards Lifesciences Corp. 100.00000000 85.00000000 USD 2023-05-19 XXXX -2461.21000000 N N N Alkermes PLC N/A 000000000 32331.00000000 NS USD 911410.89000000 0.155940466831 Long EC CORP IE N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -43.00000000 NC USD -2902.50000000 -0.00049661158 N/A DE NL N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written QIAGEN NV QIAGEN NV 100.00000000 50.00000000 USD 2023-05-19 XXXX 860.78000000 N N N Merck & Co Inc 4YV9Y5M8S0BRK1RP0397 58933Y105 236240.00000000 NS USD 25133573.60000000 4.300301042394 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -12.00000000 NC USD -11160.00000000 -0.00190945228 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Insulet Corp. Insulet Corp. 100.00000000 340.00000000 USD 2023-05-19 XXXX -718.53000000 N N N Cooper Cos Inc/The QJKMVPIGLH7530PCUE20 216648402 12951.00000000 NS USD 4835385.36000000 0.827324161494 Long EC CORP US N 1 N N Quest Diagnostics Inc 8MCWUBXQ0WE04KMXBX50 74834L100 40564.00000000 NS USD 5738994.72000000 0.981929803118 Long EC CORP US N 1 N N N STERIS PLC N/A 000000000 9590.00000000 NS USD 1834375.20000000 0.313857699276 Long EC CORP IE N 1 N N N Neurogene, Inc. Series B N/A 000000000 106790.00000000 NS USD 260567.60000000 0.044582562739 Long EC CORP US Y 3 N N N West Pharmaceutical Services Inc 5493007NKRGM1RJQ1P16 955306105 15420.00000000 NS USD 5342567.40000000 0.914101930944 Long EC CORP US N 1 N N N PTC Therapeutics Inc 549300UJLWOIWFDGB318 69366J200 6385.00000000 NS USD 309289.40000000 0.052918759201 Long EC CORP US N 1 N N N UBS AG BFM8T61CT2L1QCEMIK50 000000000 -5000.00000000 NC -49310.09000000 -0.00843685163 N/A DE US N 2 UBS AG BFM8T61CT2L1QCEMIK50 Call Written Novo Nordisk A/S Novo Nordisk A/S 1.00000000 1026.80260000 DKK 2023-04-26 XXXX -35643.70000000 N N N Waters Corp 5T547R1474YC9HOD8Q74 941848103 12225.00000000 NS USD 3785226.75000000 0.647644254564 Long EC CORP US N 1 N N N Eli Lilly & Co FRDRIPF3EKNDJ2CQJL29 532457108 98033.00000000 NS USD 33666492.86000000 5.760265398138 Long EC CORP US N 1 N N N CARBON HEALTH TECHNOLOGIES INC N/A 000000000 89892.00000000 NS USD 1066119.12000000 0.182410716280 Long EC CORP US Y 3 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -16.00000000 NC USD -3200.00000000 -0.00054751320 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Alnylam Pharmaceuticals, Inc. Alnylam Pharmaceuticals, Inc. 100.00000000 250.00000000 USD 2023-04-21 XXXX 8855.46000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -96.00000000 NC USD -20688.00000000 -0.00353967284 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Johnson & Johnson Johnson & Johnson 100.00000000 160.00000000 USD 2023-05-05 XXXX -7373.10000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -5.00000000 NC USD -4550.00000000 -0.00077849533 N/A DE IE N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written STERIS PLC STERIS PLC 100.00000000 185.00000000 USD 2023-04-21 XXXX -3361.16000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -9.00000000 NC USD -1102.50000000 -0.00018863540 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Glaukos Corp. Glaukos Corp. 100.00000000 52.50000000 USD 2023-04-21 XXXX 1648.19000000 N N N Catalent Inc N/A 148806102 20045.00000000 NS USD 1317156.95000000 0.225362755620 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -209.00000000 NC USD -2194.50000000 -0.00037547428 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Merck & Co., Inc. Merck & Co., Inc. 100.00000000 115.00000000 USD 2023-04-21 XXXX 29525.37000000 N N N IDEXX Laboratories Inc OGMTXK0LUU1HKV2P0J84 45168D104 7185.00000000 NS USD 3593074.80000000 0.614767464179 Long EC CORP US N 1 N N N Hologic Inc 549300DYP6F5ZJL0LB74 436440101 10990.00000000 NS USD 886893.00000000 0.151745507944 Long EC CORP US N 1 N N N Baxter International Inc J5OIVXX3P24RJRW5CK77 071813109 111827.00000000 NS USD 4535703.12000000 0.776049166956 Long EC CORP US N 1 N N N Bristol-Myers Squibb Co HLYYNH7UQUORYSJQCN42 110122108 39106.00000000 NS USD 2710436.86000000 0.463749987960 Long EC CORP US N 1 N N N Insitro, Series C N/A 000000000 30616.00000000 NS USD 356064.08000000 0.060921807569 Long EC CORP US Y 3 N N N NOMURA SECURITIES INTERNATIONAL INC OXTKY6Q8X53C9ILVV871 000000000 -80.00000000 NC USD -40646.80000000 -0.00695458111 N/A DE US N 2 NOMURA SECURITIES INTERNATIONAL INC OXTKY6Q8X53C9ILVV871 Call Written BioMarin Pharmaceutical, Inc. BioMarin Pharmaceutical, Inc. 100.00000000 96.50000000 USD 2023-05-12 XXXX -19545.30000000 N N N UBS AG BFM8T61CT2L1QCEMIK50 000000000 -8000.00000000 NC USD -3382.24000000 -0.00057869407 N/A DE US N 2 UBS AG BFM8T61CT2L1QCEMIK50 Call Written Bausch & Lomb Corp. Bausch & Lomb Corp. 1.00000000 17.25000000 USD 2023-04-05 XXXX 6702.55000000 N N N JP MORGAN CHASE BANK 7H6GLXDRUGQFU57RNE97 000000000 -5900.00000000 NC USD -10821.13000000 -0.00185147235 N/A DE US N 2 JP MORGAN CHASE BANK 7H6GLXDRUGQFU57RNE97 Call Written Alkermes PLC Alkermes PLC 1.00000000 27.30800000 USD 2023-05-08 XXXX -4624.36000000 N N N Gilead Sciences Inc 549300WTZWR07K8MNV44 375558103 172670.00000000 NS USD 14326429.90000000 2.451221716945 Long EC CORP US N 1 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -231.00000000 NC USD -69300.00000000 -0.01185708276 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Abbott Laboratories Abbott Laboratories 100.00000000 101.00000000 USD 2023-05-05 XXXX -21074.30000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -15.00000000 NC USD -10425.00000000 -0.00178369535 N/A DE US N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written 10X Genomics, Inc. 10X Genomics, Inc. 100.00000000 50.00000000 USD 2023-04-21 XXXX -858.66000000 N N N Options Clearing Corp. 549300CII6SLYGKNHA04 000000000 -27.00000000 NC USD -10057.50000000 -0.00172081688 N/A DE NL N 1 Options Clearing Corp. 549300CII6SLYGKNHA04 Call Written Argenx SE Argenx SE 100.00000000 400.00000000 USD 2023-04-21 XXXX 19029.84000000 N N N NOMURA SECURITIES INTERNATIONAL INC OXTKY6Q8X53C9ILVV871 000000000 -111.00000000 NC USD -30034.38000000 -0.00513881860 N/A DE US N 2 NOMURA SECURITIES INTERNATIONAL INC OXTKY6Q8X53C9ILVV871 Call Written Boston Scientific Corp. Boston Scientific Corp. 100.00000000 47.74000000 USD 2023-04-21 XXXX -12979.52000000 N N N 2023-05-01 BlackRock Health Sciences Trust Chuck Pulsfort Chuck Pulsfort Assistant Treasurer XXXX