Liquidity (Details) - USD ($) $ in Thousands |
1 Months Ended | ||||
|---|---|---|---|---|---|
Feb. 28, 2015 |
Dec. 31, 2015 |
Dec. 31, 2014 |
Dec. 31, 2013 |
Dec. 31, 2012 |
|
| Liquidity [Line Items] | |||||
| Cash and cash equivalents | $ 6,260 | $ 16,815 | $ 0 | $ 0 | |
| Marketable securities | 17,807 | $ 0 | |||
| Net proceeds to the company | $ 51,900 | ||||
| Underwriting discounts and commissions deducted | 4,200 | ||||
| Offering costs deducted | $ 3,900 | ||||
| Drug supply agreement | Affiliated Entity | |||||
| Liquidity [Line Items] | |||||
| Prepaid research and development | 11,300 | ||||
| Committed Equity Funding | |||||
| Liquidity [Line Items] | |||||
| Common stock, value, subscriptions | $ 20,000 | ||||
| Commitment letter maximum ownership percentage (more than) | 19.90% | ||||
| Committed Equity Funding First Two Draw Downs [Member] | |||||
| Liquidity [Line Items] | |||||
| Common stock, value, subscriptions | $ 2,000 |