|
Consolidated Statements of Comprehensive Loss (USD $)
In Thousands, except Per Share data, unless otherwise specified |
12 Months Ended | ||
|---|---|---|---|
|
Dec. 31, 2013
|
Dec. 31, 2012
|
Dec. 31, 2011
|
|
| Revenues | |||
| Royalty revenue | $ 2,562 | $ 3,317 | |
| Collaborative and other research and development | 14,769 | 22,976 | 19,643 |
| Total revenues | 17,331 | 26,293 | 19,643 |
| Expenses | |||
| Research and development | 42,730 | 51,464 | 57,249 |
| General and administrative | 5,220 | 6,826 | 11,981 |
| Royalty | 98 | 132 | |
| Restructuring | 1,759 | ||
| Total operating expenses | 48,048 | 60,181 | 69,230 |
| Loss from operations | (30,717) | (33,888) | (49,587) |
| Interest and other income | 93 | 222 | 413 |
| Interest expense | (4,778) | (4,666) | (3,774) |
| Gain (loss) on foreign currency derivative | 5,294 | (749) | (4,000) |
| Net loss | (30,108) | (39,081) | (56,948) |
| Basic and diluted net loss per common share | $ (0.55) | $ (0.79) | $ (1.26) |
| Weighted average shares outstanding | 55,216 | 49,474 | 45,144 |
| Unrealized loss on available for sale investments | (23) | (13) | (65) |
| Comprehensive loss | $ (30,131) | $ (39,094) | $ (57,013) |