| Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block] |
A summary of the Company's option activity related to options to employees and directors, and related information is as follows: | | | For the Nine months ended September 30, 2016 | | | | Amount of options | | | Weighted average exercise price | | | Aggregate intrinsic value | | | | | | | $ | | | $ | | | | | | | | | | | | Outstanding at beginning of period | | | 1,002,451 | | | | 2.6072 | | | | | | Granted | | | 70,667 | | | | 0.75 | | | | | | Exercised | | | - | | | | - | | | | | | Cancelled | | | (141,556 | ) | | | 4.4294 | | | | | | Outstanding at end of period | | | 931,562 | | | | 2.1894 | | | | 205,499 | | | | | | | | | | | | | | | Vested and expected-to-vest at end of period | | | 792,397 | | | | 2.1812 | | | | 181,283 |
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| Schedule of Share-based Compensation, Shares Authorized under Stock Option Plans, by Exercise Price Range [Table Text Block] |
Issuance date | | Number of warrants issued | | | Exercised | | | Forfeited | | | Outstanding | | | Exercise Price $ | | | Warrants exercisable | | | Exercisable through | | | Nov-Dec 2004 | | | 973,390 | | | | 959,734 | | | | 13,656 | | | | - | | | | 0.00075 - 0.15 | | | | - | | | | - | | | Feb-Dec 2005 | | | 203,898 | | | | 32,011 | | | | 171,887 | | | | - | | | | 2.25 - 37.5 | | | | - | | | | - | | | Feb-Dec 2006 | | | 112,424 | | | | 48,513 | | | | 63,911 | | | | - | | | | 0.075 – 22.5 | | | | - | | | | - | | | Mar-Nov 2007 | | | 180,220 | | | | - | | | | 66,887 | | | | 113,333 | | | | 2.25 - 7.05 | | | | 113,333 | | | | Mar 2017 – Oct 2017 | | | Nov 2008 | | | 6,667 | | | | - | | | | - | | | | 6,667 | | | | 2.25 | | | | 6,667 | | | | Sep-18 | | | Apr-Oct 2009 | | | 26,667 | | | | 6,667 | | | | - | | | | 20,000 | | | | 1.005 – 1.5 | | | | 20,000 | | | | Apr 2019 – Oct 2019 | | | Aug 2007- Jan 2011 | | | 2,016,667 | | | | - | | | | - | | | | 2,016,667 | | | | 3 - 4.35 | | | | 2,016,667 | | | | Nov-17 | | | Jan 2010 | | | 83,333 | | | | - | | | | 83,333 | | | | - | | | | 7.5 | | | | - | | | | - | | | Feb 2010 | | | 8,333 | | | | 8,333 | | | | - | | | | - | | | | 0.15 | | | | - | | | | - | | | Feb 2010 | | | 200,000 | | | | - | | | | 200,000 | | | | - | | | | 7.5 | | | | - | | | | - | | | Feb 2010 | | | 100,000 | | | | 100,000 | | | | - | | | | - | | | | 0.015 | | | | - | | | | - | | | Feb 2011 | | | 42,735 | | | | - | | | | 42,735 | | | | - | | | | 5.85 | | | | - | | | | - | | | Feb 2011 | | | 427,167 | | | | 63,122 | | | | 364,044 | | | | - | | | | 4.2 | | | | - | | | | - | | | Feb 2011 | | | 854,333 | | | | - | | | | 854,333 | | | | - | | | | 7.5 | | | | - | | | | - | | | Jul 2012 | | | 32,931 | | | | - | | | | 32,931 | | | | - | | | | 5.22 | | | | - | | | | - | | | Jul 2012 | | | 990,949 | | | | 687,037 | | | | 303,911 | | | | - | | | | 4.35 | | | | - | | | | - | | | Feb 2013 | | | 55,556 | | | | - | | | | 55,556 | | | | - | | | | 7.5 | | | | - | | | | - | | | April 2010-2014 | | | 12,889 | | | | 8,889 | | | | 4,000 | | | | - | | | | 0.00075 | | | | - | | | | - | | | Aug 2013 | | | 1,147,471 | | | | - | | | | 1,147,471 | | | | - | | | | 3.75 | | | | - | | | | - | | | Aug 2013 | | | 29,000 | | | | 29,000 | | | | - | | | | - | | | | 0.525 | | | | - | | | | - | | | Jun 2014 | | | 2,800,000 | | | | 2,546,667 | | | | - | | | | 253,333 | | | | 5.22 | | | | 253,333 | | | | Jun-17 | | | Jun 2014 | | | 84,000 | | | | - | | | | - | | | | 84,000 | | | | 4.5 | | | | 84,000 | | | | Jun-17 | | | Jan 2015 | | | 3,858,201 | | | | - | | | | - | | | | 3,858,201 | | | | 6.5 | | | | 3,858,201 | | | | Jun-18 | | | | | | 14,246,831 | | | | 4,489,973 | | | | 3,404,655 | | | | 6,352,201 | | | | | | | | 6,352,201 | | | | |
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